Urethral cancer

Urethral cancer is a rare type of cancer that occurs in the urethra, the tube that carries urine from the bladder out of the body. It can develop in different types of cells within the urethra and is more common in older adults and individuals assigned male at birth. Urethral cancer can be challenging to treat because it often spreads to surrounding tissues and nearby organs. Early detection and treatment are essential for the best results.

Since urethral cancer is so rare, it’s important to receive care from specialists with extensive experience. At Penn Medicine, our patients partner with a team of nationally recognized experts in urethral cancer diagnosis, treatment, and research. Our urologic cancer experts distinguish themselves by integrating the latest treatment advancements with individualized care strategies, setting us apart from other hospitals in the greater Philadelphia, Lancaster, and Princeton regions.

Types of urethral cancer

There are three types of urethral cancer:

• Urothelial carcinoma: Formerly known as transitional cell carcinoma, it’s the same type of cancer as bladder cancer and originates in the urothelial cells that line the bladder and other areas of the urinary tract.
• Squamous cell carcinoma: This type of urethral cancer forms in the cells nearest the urethral opening.
• Adenocarcinoma: This type of urethral cancer begins in the glandular cells, which are responsible for producing mucus and other fluids.

Urethral cancer symptoms

Symptoms of urethral cancer can often resemble those of other conditions. It’s important to see your doctor for an accurate diagnosis and appropriate treatment if you experience any of the following symptoms:

• Swollen lymph nodes in the groin
• Frequent urge to urinate, often resulting in little or no output
• Trouble urinating, including interruptions in urine flow
• A lump in the area between the genitals and anus
• Pain or burning during urination
• Blood in the urine, which can cause it to look red or brownish
• Discharge from the urethra
• Urinary incontinence

What is the cause of urethral cancer?

The exact cause of urethral cancer isn’t always clear, but several risk factors can increase the likelihood of developing the disease, such as smoking and certain conditions. Being aware of the risk factors and taking proactive measures can help achieve the best outcomes for urethral cancer.

Urethral cancer diagnosis at Penn Medicine

Urethral cancer is rare, and its symptoms can often mimic other conditions. At Penn Medicine, our specialists use advanced diagnostic tools to accurately detect urethral cancer, ensuring that you receive the most effective treatment possible.

Urethral cancer treatment at Penn Medicine

Effectively treating urethral cancer requires specialized expertise and training. Treatment options may include surgery, chemotherapy, radiation, and other therapies. Our team of specialists stays up to date with the latest research to develop a customized treatment plan that aims for optimal results.

Penn Medicine delivers specialized urethral cancer care

We’re home to highly trained specialists with extensive experience treating rare cancers like urethral cancer. Our team includes leading urologic oncologists who focus on urinary tract cancers, ensuring you receive the most knowledgeable and skilled care.

Partnering with us for urethral cancer care offers several key benefits:

• Multidisciplinary approach: Your care is managed by a team of experts from various fields, including urology, oncology, radiology, and pathology. This collaborative approach means that all aspects of your diagnosis and treatment are carefully considered.
• Continuity of care: We offer seamless coordination of care, with all your treatments and follow-up care managed within the same health system. This continuity ensures that you receive consistent and cohesive care throughout your cancer journey.
• Dedicated nurse navigator: From your first contact with our program, our oncology nurse navigators ensure a smooth experience. If you’re dealing with a urethral cancer diagnosis, your nurse navigator will coordinate your appointments with the appropriate specialists and guide you through what to expect and how to prepare.
• Support services: Your care team provides a wide range of supportive services for cancer to help you manage the physical, emotional, and logistical challenges of cancer treatment. This includes nutritional counseling, support groups, pain management, and access to social workers.