The Male Infertility Program at Penn Medicine offers a truly innovative and comprehensive approach to building a family. We seamlessly integrate two key departments: our Reproductive Urology Center and Penn Fertility Care. This collaboration boosts your chances of having a biological child by caring for you and your partner as a team. You receive male fertility treatment that's completely personalized for your family building goals.

Male Infertility Program: The Penn Medicine Advantage

Our experts have helped thousands of people have a biological child, even those with no detectable sperm (azoospermia) or a low sperm count. We can do this because we have:

  • Coordinated care model: Our program works closely with the female fertility experts at Penn Fertility Care. We work together to coordinate a comprehensive, patient-oriented treatment plan for couples interested in future family building. This includes intrauterine insemination (IUI) or in-vitro fertilization (IVF) services. This coordination offers the best options to achieve your family planning goals.
  • Microsurgery for sperm retrieval: Our world-leading surgeon performs delicate microsurgery to retrieve sperm in men with azoospermia (no detectable sperm in the ejaculate). Our surgeon uses a high-powered microscopeto find and collect tiny pockets of sperm in men with a severe sperm production issue (non-obstructive azoospermia). We also offer minimally invasive sperm retrieval approaches for men with obstructive azoospermia.
  • Fellowship-trained urologists: Our doctors specialize in all aspects of male reproductive medicine and surgery. Their advanced training allows them to diagnose and treat frequently overlooked causes of low sperm count or fertility difficulties. Meet our male infertility specialists.
  • On-site andrology labs: Our labs specialize in semen analyses and infertility in males. Because they're on-site, your sperm sample remains fresh and avoids damage during travel. Our trained andrology technicians provide highly accurate evaluations for infertility so we can craft the best care plan for you. On-site labs are located at Penn Internal Medicine University City, Penn Medicine Washington Square, and Penn Medicine Radnor.
  • Advanced male fertility testing: We have the most advanced equipment and laboratory to provide a fast, accurate diagnosis. This can be done the same day of your appointment. We provide hormone and genetic male fertility tests to provide a complete picture of your fertility potential.

Specialized Male Infertility Treatment

Penn offers the region's most advanced and comprehensive male fertility treatment options dedicated to disorders that affect male reproductive health.

Azoospermia services

Our experts treat sperm blockages, sperm production issues and hormonal conditions that lead to low or no sperm count. Learn more about our leading-edge azoospermia treatments.

Fertility Preservation Program

We provide comprehensive fertility preservation options for those who wish to preserve biological fertility before any medical or surgical treatment. Read more about our Fertility Preservation Program.

Intrauterine insemination (IUI)

IUI can increase the chances of pregnancy with specialized sperm washing and placement in the uterus. Learn about intrauterine insemination, which was pioneered by doctors at Penn.

Paraplegics and male infertility services

Many men with paraplegia or spinal cord injury (SCI) can have children, but need specialized care to do so. Our doctors use advanced techniques to retrieve sperm.

We also partner with our female Fertility Care program to carefully coordinate your sperm collection with your partner's fertility procedure. Learn more about our services for male infertility in paraplegics.

Varicocele services

Varicoceles are large, dilated veins in the scrotum that may cause infertility in men. Our varicocele services deliver advanced microsurgical treatments that boost your chances of having a biological child.

Vasectomy reversal

A previous vasectomy doesn't have to be the end of your fertility. Our advanced microsurgical techniques can restore your ability to have a biological child. Learn more about our specialized vasectomy reversal and sperm extraction procedures.

Make an Appointment

Call 800-789-7366 or request a callback.

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Treatments and Procedures

We offer leading-edge treatments for men and couples looking to build a family.