What is a seizure?

A seizure is a brief disruption in the brain’s normal electrical activity. The brain’s nerve cells send signals to communicate with your body and control how it works. During a seizure, those signals become sudden and disorganized, interrupting normal brain function for a short time. Some people have a single seizure in their lifetime. Others have a medical condition, such as epilepsy, that makes them more likely to experience repeated seizures.

At Penn Medicine, people with seizures receive care from specialists experienced in diagnosing and treating seizure disorders. Our Comprehensive Epilepsy Center is a Level 4 epilepsy center—the highest designation from the National Association of Epilepsy Centers—offering advanced testing and treatment for complex seizure conditions.

Seizure symptoms

Signs and symptoms of seizures vary depending on the area of the brain affected and the type of seizure. Some seizure symptoms are obvious, while others might not be noticeable at all.

People with seizures may experience one or more of the following symptoms:

  • Abnormal or unpleasant taste or smell
  • Hearing or seeing things that are not there
  • Strange thoughts or experiences, such as déjà vu or sudden behavioral changes
  • Involuntary movements of the arms or legs
  • Spells of staring or unresponsiveness during which the person has difficulty communicating and may remember nothing
  • Lip smacking or repetitive movements, for example picking or grasping movements
  • Whole-body stiffening or shaking
  • Drooling or frothing from the mouth
  • Loss of bladder or bowel control

Seizure triggers

Certain events or exposures called triggers may set off the abnormal electrical brain activity that causes seizures.

Common seizure triggers include:

  • Alcohol or drug use or withdrawal
  • Certain foods and medications
  • Dehydration, physical exertion, or malnutrition
  • Flashing lights or patterns (photosensitivity)
  • High environmental temperatures
  • Hormonal changes (such as those during menstruation)
  • Illness or fever
  • Sleep disturbance or stress

Seizure types

Doctors categorize seizures into two main types—generalized seizures and focal seizures. The type of seizure depends on what part of the brain is affected and the symptoms a person has during the seizure.

What causes a seizure?

All seizures are caused by abnormal electrical activity in the brain. In some cases, the cause of seizures is unknown. In other cases, the abnormal activity can be caused by different factors.

How are seizures diagnosed?

Some seizures have obvious symptoms, but others are subtle. Even when seizure symptoms are obvious, the cause often isn't. Precise diagnostic testing is the only true way to determine the cause of seizures.

We begin by reviewing your medical and family health history. You will be asked questions about your seizures, including how often they occur, what seems to trigger them, and what you experience during your seizures. Since many people with seizures do not remember them, we also ask family members or other witnesses what they observe when you have a seizure.

Your doctor will likely order brain imaging and other tests to pinpoint where abnormal electrical activity is happening in the brain and what is causing it.

Seizure treatment at Penn Medicine

The specialists at Penn Medicine's Comprehensive Epilepsy Center offer a variety of treatment options.

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Patient stories

Essential tremor patient finds relief

Essential tremor patient finds relief

When his essential tremor symptoms became severe, Jim McDevitt turned to Dr. Iahn Cajigas and the team at Penn Medicine for help.

Actress returns to stage after struggling with seizures

Actress returns to stage after struggling with seizures

Her seizure medications weren't helping, so actress Hannah Parke turned to Penn Medicine for the relief she needed to get back onstage.

Epilepsy surgery gives patient a new lease on life

Epilepsy surgery gives patient a new lease on life

Minimally invasive laser interstitial thermal therapy (LITT) surgery reduced the epilepsy symptoms a patient had experienced for more than 30 years.

A minimally invasive solution to seizures

A minimally invasive solution to seizures

When Betsy Berlin's seizures returned after 24 years, medication was no longer helping. A minimally invasive procedure gave her the relief she needed.

A cold, a coma, and a Christmas miracle

A cold, a coma, and a Christmas miracle

A young mother was diagnosed with a rare, deadly brain disorder. During her month-long coma, Penn Medicine’s bold care saved her life.

Essential tremor treatment rekindles a man's passion for art

Essential tremor treatment rekindles a man's passion for art

A tremor forced Mike Burton to abandon his love of art. Now he’s painting again, thanks to a noninvasive procedure that eliminated his shaking.

Essential tremor patient finds relief

Essential tremor patient finds relief

When his essential tremor symptoms became severe, Jim McDevitt turned to Dr. Iahn Cajigas and the team at Penn Medicine for help.

Actress returns to stage after struggling with seizures

Actress returns to stage after struggling with seizures

Her seizure medications weren't helping, so actress Hannah Parke turned to Penn Medicine for the relief she needed to get back onstage.

Epilepsy surgery gives patient a new lease on life

Epilepsy surgery gives patient a new lease on life

Minimally invasive laser interstitial thermal therapy (LITT) surgery reduced the epilepsy symptoms a patient had experienced for more than 30 years.

A minimally invasive solution to seizures

A minimally invasive solution to seizures

When Betsy Berlin's seizures returned after 24 years, medication was no longer helping. A minimally invasive procedure gave her the relief she needed.

A cold, a coma, and a Christmas miracle

A cold, a coma, and a Christmas miracle

A young mother was diagnosed with a rare, deadly brain disorder. During her month-long coma, Penn Medicine’s bold care saved her life.

Essential tremor treatment rekindles a man's passion for art

Essential tremor treatment rekindles a man's passion for art

A tremor forced Mike Burton to abandon his love of art. Now he’s painting again, thanks to a noninvasive procedure that eliminated his shaking.

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