Testicular cancer treatment

Our testicular cancer treatments

Surgery to remove the affected testicle can cure testicular cancer. But sometimes, you need other treatments if the cancer has spread or to prevent its return.

The best treatments for you are often highly personal — and our doctors take the time to make sure you understand the risk and benefits of all your options.

Our testicular cancer treatments include:

Proton therapy for testicular cancer

At Penn Medicine, we offer the latest technologies that not only cure cancers — they reduce the risk of testicular cancer treatment side effects that affect your quality of life. Proton therapy is one of these advanced tools.

What is proton therapy for testicular cancer?

Proton radiation therapy is a highly accurate form of radiation therapy, a noninvasive treatment that uses high-energy radiation to kill cancer cells. Proton therapy uses positively charged atoms called protons.

Because doctors have tight control over proton beams, they can closely target cancer cells and protect healthy tissues. Learn more about proton therapy.

Benefits of proton radiation for stage 2 testicular cancers

The first treatment for testicular cancer is usually surgery to remove the affected testicle. But if the cancer has spread beyond the testicle, your doctor may recommend radiation.

Stage 2 testicular cancers have spread beyond the testicle to at least one lymph node. Proton therapy is particularly suited for stage 2 testicular cancers because it:

  • Reduces long-term testicular cancer treatment side effects: Long-term treatment side effects can appear decades after cancer treatment. Proton therapy delivers lower, more precise doses of radiation while avoiding healthy cells. It can reduce the radiation dose to healthy surrounding tissues by 50 to 70 percent. This precision may lead to fewer or milder long-term side effects, such as the development of a second cancer as you age.
  • Lowers radiation exposure: When you get radiation for testicular cancer, doctors direct the radiation beams at lymph nodes in the abdomen (belly) — not the testicles. The treatment area is one of the largest among all cancers treated with radiation. Because it’s so large, there is a risk of radiation exposure to tissues around the belly and pelvis. Proton therapy eliminates this risk.
  • Treats affected lymph nodes: Testicular cancer-affected lymph nodes run along the center of the body. The more central the cancer is, the better it is for proton therapy.
National Cancer Institute Designated Comprehensive Cancer Center badge on top of shot of hospital

Rated “exceptional” by The National Cancer Institute

Penn Medicine’s Abramson Cancer Center is a world leader in cancer research, patient care, and education. Our status as a national leader in cancer care is reflected in our continuous designation as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since 1973, one of 7 such centers in the United States. The ACC is also a member of the National Comprehensive Cancer Network, one of a select few cancer centers in the U.S., that are working to promote equitable access to high-quality, advanced cancer care.

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