Testicular cancer surgery

Surgery to remove the affected testicle is usually the first treatment for testicular cancer. Depending on the stage of testicular cancer, it can be a cure.

At Penn Medicine, our world-renowned surgeons treat many patients each year. High-volume programs like ours offer patients more experience and expertise and better outcomes.

Radical inguinal orchiectomy (testicle removal surgery)

Radical inguinal orchiectomy removes testicles affected by cancer.

You may also need adjuvant (after surgery) chemotherapy or radiation even if orchiectomy removes all visible cancer. This additional treatment ensures that we kill any remaining cancer cells. As an alternative, your doctor may recommend testicular cancer active surveillance instead.

Radical inguinal orchiectomy: What to expect

During the procedure, your surgeon:

  1. Makes an incision similar to an inguinal hernia incision in your groin area
  2. Removes one or both testicles and the spermatic cord (collection of vessels, nerves and ducts that supply the testicles with blood and sperm)
  3. Sends the tumor tissue to our pathologists so they can analyze it under a microscope

The entire procedure takes an hour or less. Usually, you can go home the same day as your procedure. You can expect to fully recover in two to four weeks.

Orchiectomy does not affect your ability to get an erection and have intercourse.

Retroperitoneal lymph node dissection (RPLND)

Retroperitoneal lymph node dissection is surgery to remove the lymph nodes where testicular cancer usually spreads (metastasizes). These lymph nodes are located around the:

  • Aorta (major blood vessel)
  • Inferior vena cava (major blood vessel)
  • Back of the abdomen

Surgeons perform RPLND after orchiectomy. It is a standard treatment for stage I and stage II nonseminomas, one type of testicular cancer. It is also commonly used after chemotherapy for NSGCT. Nonseminomas typically grow faster than seminomas.

Not everyone needs this surgery. Our testicular cancer experts pool their expertise to make the most appropriate treatment recommendation for you. We walk you through the potential benefits and risks of retroperitoneal lymph node dissection — and any treatment alternatives — so you can make informed decisions about your care.

National Cancer Institute Designated Comprehensive Cancer Center badge on top of shot of hospital

Rated “exceptional” by The National Cancer Institute

Penn Medicine’s Abramson Cancer Center is a world leader in cancer research, patient care, and education. Our status as a national leader in cancer care is reflected in our continuous designation as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since 1973, one of 7 such centers in the United States. The ACC is also a member of the National Comprehensive Cancer Network, one of a select few cancer centers in the U.S., that are working to promote equitable access to high-quality, advanced cancer care.

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