Ashish Thakrar, MD, MSHP is an Assistant Professor of Medicine in the Division of General Internal Medicine at the University of Pennsylvania’s Perelman School of Medicine. He is an internist and an addiction medicine specialist. Dr. Thakrar’s research focuses on expanding and adapting evidence-based treatment for substance use disorders in the era of fentanyl, xylazine, and other synthetic drugs. He works clinically as a hospital-based addiction consult physician and as an outpatient primary care and addiction treatment physician. Dr. Thakrar earned his MD and MS in Health Policy Research at the University of Pennsylvania’s Perelman School of Medicine and he is a graduate of the Osler Medicine Residency (Urban Health Primary Care Track) at Johns Hopkins Hospital and the Addiction Medicine Fellowship at Johns Hopkins Bayview.

Areas of Expertise | Clinical Trials, Implementation Science, Opioid Epidemic, Qualitative Methods

Clinical Areas | Addiction Medicine, General Internal Medicine

Selected Publications:

Thakrar AP, Lowenstein M, Greysen SR, Delgado MK. Trends in Before Medically Advised Discharges for Patients with Opioid Use Disorder, 2016-2020. JAMA. Published online December 4, 2023.

McFadden R, Wallace-Keeshen S, Petrillo K, Hosey R, Neuschatz R, McNulty K, Thakrar AP. Xylazine-Associated Wounds: Clinical Experience from a Low-Barrier Wound Care Clinic in Philadelphia. Journal of Addiction Medicine. Published online October 3, 2023

Thakrar AP, Pytell JD, Stoller KB, Walters V, Weiss RD, Chander G. Transitioning off methadone: A qualitative study exploring why patients discontinue methadone treatment for opioid use disorder. Journal of Substance Use and Addiction Treatment. 2023; 150(209).

Thakrar AP, Uritsky TJ, Christopher C, Winston A, Ronning K, Sigueza AL, Caputo A, Olenik J, Perrone J, Delgado MK, Lowenstein M, Compton P. Short-Acting Opioid Agonist Therapy (sOAT) for Hospitalized Patients with Opioid Use Disorder: A Case Series. Addiction Science & Clinical Practice. 2023;18(13). 

Thakrar AP. Short-Acting Opioids for Hospitalized Patients With Opioid Use Disorder. JAMA Internal Medicine. 2022;182(3):247-248.

Thakrar AP, Alexander GC, Saloner B. Buprenorphine Use in Jails and Prisons in the US, 2015 to 2021. JAMA Network Open. 2021;4(12);e2138807.

Thakrar AP, Furfaro D, Keller S, Graddy R, Buresh M, Feldman L. A Resident-Led Intervention to Increase Initiation of Buprenorphine Maintenance for Hospitalized Patients With Opioid Use Disorder. Journal of Hospital Medicine. 2021;16(6):339-344.

Visit Dr. Thakrar's Google Scholar page to view more publications

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