Sleep keeps neuroscientist Marcos Frank awake, studying the importance of slumber during early life. Building on his research showing that the brain during sleep is fundamentally different from the brain during wakefulness, Frank an associate professor of Neuroscience at the Perelman School of Medicine at the University of Pennsylvania has found that cellular changes in the sleeping brain may promote the formation of memories. In the newest study from the lab, published in the March 1 issue of Current Biology, the team found that sleep is associated with increased brain protein synthesis and transcription of messenger RNAs.

New research indicates that in recent years orthopaedic surgeons have seen a dramatic surge in the number of Baby Boomers suffering from rheumatoid arthritis, osteoarthritis, or injury to the joint – often resulting from increased activities such as marathon running, swimming, or even power walking. According to the federal Agency for Healthcare Research and Quality, knee replacements nearly tripled in people ages 45 to 64 between 1997 and 2009. Though still less common in younger patients, current estimates suggest that more than half a million Americans in their 50s have had the procedure. Based on current trends, operations in that age group are expected to increase.

To celebrate February as American Heart Month, the News Blog is highlighting some of the latest heart-centric news and stories from all parts of Penn Medicine. This month marks the five-year anniversary of Penn Medicine’s first implantation of a temporary total artificial heart (TAH) in a patient suffering from end-stage...

Would you be able to find an automated external defibrillator if someone’s life depended on it? Despite an estimated one million AEDs scattered around the United States, the answer, all too often when people suffer sudden cardiac arrests, is no. In a Perspective piece published online this week in the journal Circulation: Cardiovascular Quality Outcomes, Penn Medicine emergency physician Dr. Raina Merchant outlines the tremendous potential associated with greater utilization of AEDs in public places. In cases of ventricular fibrillation – a wild, disorganized cardiac rhythm that leaves the heart unable to properly pump blood through the body, which is the leading cause of sudden cardiac death – quick use of an AED and CPR improve a patient’s chance of surviving by more than 50 percent.

To celebrate February as American Heart Month, the News Blog is highlighting some of the latest heart-centric news and stories from all parts of Penn Medicine. Hot flashes. Night sweats. Sleep disturbances. Mood swings. Irregular and racing hearts. These are all signs of menopause setting in, the time in a...

Nothing beats mother’s milk when it comes to helping infants thrive. It contains all the vitamins and nutrients a baby needs in its first six months of life. Breast milk is especially good for premature babies because it is also filled with disease-fighting substances and is much easier for their...

To celebrate February as American Heart Month, the News Blog is highlighting some of the latest heart-centric news and stories from all parts of Penn Medicine. The flowers and cards have all been delivered. The chocolates were devoured and Cupid can now take his annual break. But just because Valentine’s...