News Releases

More than two-thirds of pancreatic cancer patients harboring genetic mutations saw their tumor stop growing or shrink substantially after being switched from intensive chemotherapy to the PARP inhibitor rucaparib as a maintenance therapy, researchers from the Abramson Cancer Center at the University of Pennsylvania reported online today in the Journal of Clinical Oncology.

The latest generation of personal alcohol breath testing devices pair with smartphones. While some of these devices were found to be relatively accurate, others may mislead users into thinking that they are fit to drive, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.

New research performed in mice models at Penn Medicine shows, mechanistically, how the infant lung regenerates cells after injury differently than the adult lung, with alveolar type 1 cells reprograming into alveolar type 2 cells, promoting cell regeneration.

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

When evaluating the opioid crisis, research reveals that external factors – such as the volume of pre-filled syringes, or a default number of opioid tablets that could easily be ordered at discharge for the patient – can shift prescribing and compel emergency department (ED) physicians to administer or prescribe greater quantities of opioids.

It turns out that not all build-ups of tau protein are bad, and a team of researchers from the Perelman School of Medicine at the University of Pennsylvania developed a method to show that. Using mammalian cell models, the researchers combined extremely high-resolution microscopy with machine learning to show that tau actually forms small aggregates when a part of the body’s normal physiology.

A new service piloted at Penn Medicine allowed a proportion of patients to avoid hospitalization by providing them with greater support after visiting the emergency department.

The Pennsylvania Department of Health’s Commonwealth Universal Research Enhancement (CURE) program announced it will award a $3.5 million grant to Penn Medicine researchers and community partners to address the underrepresentation of Black adults in Alzheimer’s Disease research.