News Releases

Two faculty members of the University of Pennsylvania School of Medicine, Yvonne Paterson, PhD, and Susan R. Weiss, PhD, have been named Fellows of the American Association for the Advancement of Science (AAAS).

Armed with research concluding that psoriasis is associated with an increased risk of heart attacks and other cardiovascular conditions, Joel M. Gelfand, MD, MSCE, Assistant Professor of Dermatology at the University of Pennsylvania School of Medicine and colleagues released an editorial consensus in the American Journal of Cardiology today, calling for psoriasis patients to be educated about and screened for cardiovascular risk factors. Dr. Gelfand's latest research estimates that, in addition to the seven million Americans adults diagnosed with psoriasis, as many as 3.6 million Americans are living with active, undiagnosed psoriasis, unaware of the associated cardiovascular risk.

Researchers at theUniversity of Pennsylvania School of Medicine have discovered stem cells in the esophagus of mice that were able to grow into tissue-like structures and when placed into immune-deficient mice were able to form parts of an esophagus lining. The investigators report their findings online this month in the Journal of Clinical Investigation.

Penn Presbyterian Medical Center is the only hospital in Philadelphia to be selected as one of the nation's "100 Top Hospitals" for cardiovascular care by Thomson Reuters, a leading news and information company. Each year, this award for cardiovascular services objectively measures performance on key criteria at the nation's top-performing acute-care hospitals. This is the sixth year that Penn Presbyterian has been recognized with this honor.

A new study from the Abramson Cancer Center and Department of Psychiatry in the University of Pennsylvania School of Medicine shows that smokers who carry a particular version of a gene for an enzyme that regulates dopamine in the brain may suffer from concentration problems and other cognitive deficits when abstaining from nicotine - a problem that puts them at risk for relapse during attempts to quit smoking. The findings, newly published in the journal Molecular Psychiatry, pave the way to identify novel medications to treat nicotine addiction.

During the busy holiday season, three Penn Medicine locations will pause to remember the friends, family and loved ones by lighting trees in their honor. Penn Wissahickon Hospice, a division of the Penn Home Care & Hospice Service and part of the University of Pennsylvania Health System, holds the Light Up a Life ceremony annually to honor the people who have brightened and enriched the lives of others. Each light on the tree is dedicated in honor or memory of a patient, friend or loved one.

A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has discovered a key molecular partnership that coordinates body rhythms and metabolism. Lazar and his colleagues, including the study's first author, Penn Veterinary Medicine doctoral student Theresa Alenghat, studied a protein called NCoR that modulates the body's responses to metabolic hormones. They engineered a mutation into mice that prevents NCoR from working with an enzyme that is normally its partner, HDAC3. These animals showed changes in the expression of clock and metabolic genes, and were leaner, more sensitive to insulin, and on different sleep-wake cycles than controls.

Researchers at the University of Pennsylvania School of Medicine have found an association between the genetics of donor-recipient matches in kidney transplants and complications during the first week after transplantation. The team, led by Malek Kamoun MD, PhD, Professor of Pathology and Laboratory Medicine and Director of the Clinical Immunology and Histocompatibility Laboratory, and Harold Feldman MD, MSCE, Professor of Medicine and Epidemiology, has shown that small differences in the building blocks of cell-surface proteins used to match donors and recipients for deceased-donor kidney transplantation was associated with an increased risk for delayed allograft function, or DGF.

Haig H. Kazazian, Jr., M.D., Seymour Gray Professor of Molecular Medicine in Genetics at the University of Pennsylvania School of Medicine, received the American Society of Human Genetics (ASHG) Allan Award at the Society's 58th Annual Meeting, which was held this month in Philadelphia.

PENN Medicine announced today the creation of the Clyde F. Barker Transplant House, a 'home away from home' designed to help ease the unique economic and emotional stresses of transplant families. Modeled after the Ronald McDonald Houses and named for the physician who performed the first kidney transplant at the Hospital of the University of Pennsylvania in 1966, the Barker Transplant House will be located at 3930 Spruce Street on Penn's campus and will offer comfortable, convenient accommodations in a supportive community setting - all at a nominal cost.