Description of Research Expertise

Dr. Michael J. LaRiviere is an attending radiation oncologist at the Children's Hospital of Philadelphia and the University of Pennsylvania. He did his undergraduate work in neuroscience at Amherst College, medical school at Emory University, and residency at the University of Pennsylvania. He treats pediatric patients and adult patients with hematologic malignancies, using conventional photon radiotherapy, stereotactic body radiotherapy, proton therapy, reirradiation, total skin electron therapy, and total body irradiation. Dr. LaRiviere leads research programs in translational pediatric and hematologic radiation oncology, including preclinical work with FLASH radiotherapy and clinical trials to understand the interactions between immunotherapy and radiation, and chimeric antigen T-cell (CART) therapy and radiation. Dr. LaRiviere has received research funding from the Radiological Society of North America to explore how 3D-printing can be used to improve oncology education for medical students. He is a member of the Children's Oncology Group (COG), International Society of Paediatric Oncology (Société Internationale d'Oncologie Pédiatrique - SIOP), Paediatric Radiation Oncology Society (PROS), International Lymphoma Radiation Oncology Group (ILROG), and University of Pennsylvania Radiation Oncology Quality Assurance/Quality Improvement Committee.

Selected Publications

Jiang C, Kim M, Han X, Chelius M, Hoover T, Kersun L, Reilly AF, Hubbeling H, Cummings E, Kurtz G, Hill-Kayser C, Plastaras JP, LaRiviere MJ: Outcomes of proton therapy to infradiaphragmatic sites in pediatric patients with Hodgkin lymphoma Pediatric Blood & Cancer 71 (12): e31290,2024.

Kostopoulos N, Costabile F, Krimitza E, Beghi S, Goia D, Perales-Linares R, Thyfronitis G, LaRiviere MJ, Chong EA, Schuster SJ, Maity A, Koumenis C, Plastaras JP, Facciabene A: Local Radiation Enhances Systemic CAR T Cell Efficacy by Augmenting Antigen Cross-Presentation and T-cell Infiltration Blood Advances 8 (24): 6308-6320,2024.

Dreyfuss A, Ganesan N, Alencar AJ, Boardman AP, Caron P, Chang T, Davey T, David KA, Dogan A, Epstein-Peterson ZD, Falchi L, Fregonese B, Ghione P, Hamlin PA, Horowitz S, Imber BS, Intlekofer AM, Isrow D, Joffe E, Johnson WT, Kumar A, LaRiviere M, Lue JK, Luttwak A, McNicholas M, Moore Z, Munayirji B, Noy A, Owens C, Palomba ML, Patel J, Plastaras JP, Santarosa AM, Schoder H, Shah GL, Steiner RE, Stuver R, Svoboda Jm Torka P, Vardhana SA, Zelenetz AD, Salles G, Yahalom J, Moskowitz CH, Moskowitz A: Pembrolizumab and Involved Site Radiation Therapy Alone As an Alternative to Transplant in Patients with Localized Failure Following Chemotherapy for Hodgkin Lymphoma: A Prospective Multicenter Phase II Study Blood 144 (Suppl1): 4434,2024.

Schneider M, Chong EA, Barta SK, Nasta SD, Svoboda J, Carter J, Cook MR, Hossain N, Schuster SJ, Difilippo H: Real-World Outcomes of Early Relapsed/Refractory Large B Cell Lymphoma Patients Treated with 2nd Line CAR T Therapy Blood 144 (Suppl 1): 5123,2024.

Elghawy O, Yang AG, Sussman JH, Thomas CJ, Carter JS, Landsburg DJ, Svoboda J, Kim E, Rook AH, Chung J, Villasenor-Park J, Plastaras JP, LaRiviere M, Hubbeling H, Chelius M, Nasta SD, Chong EA, Schuster SJ, Barta SK: Retrospective cohort study of novel oral agents lenalidomide and duvelisib for relapsed or refractory mycosis fungoides and Sézary syndrome Journal of the American Academy of Dermatology S0190-9622 (24): 03212-2,2024.

Byrd B, Zhu Y, Alexander DA, Chelius M, Freedman GM, LaRiviere MJ, Plastaras JP, Zhu T: Initial Clinical Experience of Cherenkov Imaging in Sub-Total Total Skin Electron Therapy Identifies Opportunities to Improve Daily Set-Up QA International Journal of Radiation Oncology, Biology, Physics 120 (2): S20,2024.

Konski XAA, Iocolano M, Yegya-Raman N, Cohen R, Langer C, Friedes C, Cengel KA, Levin WP, LaRiviere MJ, Bradley JD: Income Inequality in Patients (Pts) with Locally Advanced (LA) Non-Small Cell Lung Cancer (NSCLC) Receiving Proton BeamTherapy International Journal of Radiation Oncology, Biology, Physics 120 (2): e35,2024.

Chelius, M, Cohen, L, Jiang, C, Baron, J, Mallon, J, Tierney, A, Hubbeling, HG, Hossain, NM, Rook, A, Villasenor-Park J, Samimi S, Kim E, Plastaras JP, Barta S, LaRiviere M: The Impact of Standard vs. Hypofractionated Total Skin Electron Beam Therapy (TSE) on Cytopenias in Mycosis Fungoides/Sezary Syndrome (MF/SS) International Journal of Radiation Oncology, Biology, Physics 120 (2 Suppl 1): e614,2024.

Chelius M, Baron J, Yegya-Raman N, Chong E, Nasta SD, Landsburg DJ, Barta S, Svoboda J, Schuster S, LaRiviere MJ, Plastaras JP, Chong EA, Hubbeling HG: Radiation in Combination with Bispecific Therapy Does Not Suggest Excess Toxicity in B-Cell Lymphomas International Journal of Radiation Oncology, Biology, Physics 120 (2 Suppl 1): e614-e615,2024.

Baron JA, Wright CM, Dreyfuss AD, Chong EA, Svoboda J, LaRiviere MJ, Jones JA, Maity A, Plastaras JP, Paydar I, Maxwell R: Radiation Therapy Dose Response in Bulky Relapsed/Refractory Large B-Cell Lymphoma Practical Radiation Oncology 14 (5): e362-e372,2024.

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Academic Contact Information

Perelman Center for Advanced Medicine
3400 Civic Center Blvd., PCAM 2 West
Philadelphia, PA 19104
Phone: 215-615-7239
Patient appointments: 800-789-7366