William J. Chapin, MD, MSCE

Medical Oncology

5.0 with 154 ratings

Sees patients age 18 and up

William J. Chapin, MD, MSCE

Medical Oncology

5.0 with 154 ratings

Sees patients age 18 and up

Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Dr. Chapin is a Penn Medicine physician.

Call 800-789-7366 Request Appointment

Abdominal Cancer
Abdominal Cancer Chemotherapy
Anal Cancer
Anal Cancer Chemotherapy
Anorectal Cancer
Anorectal Cancer Chemotherapy
Appendiceal Cancer (Appendix Cancer)
Appendiceal Cancer Chemotherapy
Appendiceal Carcinoid
Bile Duct Cancer (Cholangiocarcinoma)
Biliary Tract Cancer Chemotherapy
Cancer Immunotherapy
Carcinoid of the Stomach
Carcinoid Tumor of Pancreas
Carcinoid Tumors
Chemotherapy for Cancer
Colon Cancer
Colon Cancer Chemotherapy
Colorectal Cancer Chemotherapy
Esophageal Cancer
Esophageal Cancer Chemotherapy
Esophagogastric Junction Cancer
Gallbladder Cancer
Gallbladder Cancer Chemotherapy
Gallbladder Mass
Gastrointestinal Cancer (GI Cancer)
Gastrointestinal Stromal Tumors (GIST)
Hepatobiliary Malignancies
Hereditary Colon Cancer
Insulinoma
Liver Cancer
Liver Cancer Chemotherapy
Lynch Syndrome
Malignant Neoplasm of Pancreatic Duct
Malignant Tumor of Extrahepatic Bile Duct
Metastatic Colorectal Cancer
Neuroendocrine Tumor
Pancreatic Cancer
Pancreatic Cancer Chemotherapy
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)
Pseudomyxoma Peritonei
Rectal Cancer
Small Bowel Cancer
Small Intestine Cancer
Small Intestine Cancer Chemotherapy
Squamous Cell Carcinoma of the Esophagus
Stomach Cancer (Gastric Cancer)
Stomach Cancer Chemotherapy
Targeted Therapy

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Programs and Centers

Penn Medicine's programs and centers combine doctors from many disciplines to coordinate care from start to finish. Dr. Chapin is part of these programs:

Penn Gastrointestinal Cancer Program
Penn Liver Cancer Program

Board Certification

Internal Medicine, 2019
Medical Oncology, 2022

Education and Training

Medical School: University of Chicago
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania

Primary Location

Abramson Cancer Center Perelman 2nd Floor West

Perelman Center for Advanced Medicine
West Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104

A facility of the Hospital of the University of Pennsylvania

Map Call 800-789-7366

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Penn Medicine Hospital Privileges

Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Overall Ratings

out of 5 ; Ratings;

The Patient Satisfaction Rating is an average of all responses to the care provider related question shown above from our internal platform, PMX Feedback. Responses are measured on a scale of 1 to 5 with 5 being the best score. Scores reflect either the most recent 12 months of surveys or the most recent 30 surveys overall. Data is updated monthly and comments remain on the profile for 12 months.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Patients that are treated in outpatient or hospital environments may receive different surveys.

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Aetna US Healthcare
Amerihealth Caritas
Amerihealth Caritas Medicare
Centivo Health Plan
Cigna
Cigna HealthSpring
Clover Health Plan
Devon Health Services (Americare)
Gateway Health Plan
Geisinger Health Plan
Geisinger Medicaid
Global Medical Management
HealthAmerica / HealthAssurance, a Coventry Plan
HealthPartners
HealthPartners Medicare
HealthSmart
Highmark Blue Shield
Homestead Smart Health Plans/Claim Watcher
Horizon Blue Cross Blue Shield of New Jersey
Humana / Choicecare

Humana / Medicare
Imagine Health 360
Independence Blue Cross (Keystone East)
Keystone First
Keystone First Medicare
NJ Medicaid
NJ Qualcare
Oscar Health Plan of PA
Oxford Health Plan
PA Health and Wellness (Centene) Medicare
PA Medicaid
PA Medicare
Provider Partners Health Plan
Rail Road Medicare / Palmetto GBA
Tricare
United Healthcare
UnitedHealthcare Community Plan
US Family Health Plan
Veterans Choice Program

Selected Publications

Margalit O, Stemmer A, Chapin WJ, Schacham-Shmueli E, Kopetz S, Andre T, Overman MJ, Pietrantonio F, Boursi B: Duration of Immunotherapy in dMMR/MSI-H Metastatic Colorectal Cancer Patients European Journal of Cancer : 114336,2024.

Chapin WJ, Hwang W, Mamtani R, O’Hara MH: Real-world uptake and effectiveness of triplet versus doublet chemotherapy with bevacizumab in patients with metastatic colorectal cancer in the United States ESMO Gastrointestinal Oncology 5 : 100087,2024.

Chapin WJ, Hwang W, Mamtani R, O’Hara MH: Low- vs High-Dose 5-FU in Triplet Chemotherapy Plus Bevacizumab for Patients With Colorectal Cancer JAMA Netw Open 7 (7): e2424855,2024.

Rathore S, Reiss KA, Teitelbaum UR, Chapin WJ: Exploring the association of smoking status with clinical outcomes in patients with mPDAC treated on a clinical trial of maintenance niraparib plus immune checkpoint blockade. Journal of Clinical Oncology 42 (suppl 16): Abstract e16302,2024.

William Joseph Chapin, Wei-Ting Hwang, Ronac Mamtani, and Mark H. O'Hara: Real-world comparison of low- versus high-dose continuous 5FU infusion in patients receiving triplet chemotherapy plus bevacizumab for newly diagnosed metastatic colorectal cancer (mCRC). Journal of Clinical Oncology 42 (3_suppl): 62-62,2024.

William J Chapin, Ryan C Massa, Jennifer R Eads: Defining the Role of Neoadjuvant Therapy for Gastroesophageal Cancers Advances in Oncology : 2024.

William Joseph Chapin, Wei-Ting Hwang, Ronac Mamtani, Mark H O'Hara: Real-world comparison of triplet-versus doublet-chemotherapy with bevacizumab in patients with newly diagnosed metastatic colorectal cancer (mCRC). Journal of Clinical Oncology 41 (16_suppl): 3574-3574,2023.

William Joseph Chapin, Parul Agarwal, Lisa DiCicco, Rayleigh Palmer, Nadia Cenou, Alexander Chan Chi Huang, Thomas Benjamin Karasic: Phase II trial of XmAb20717 (vudalimab) in patients with advanced biliary tract cancers. Journal of Clinical Oncology 41 (16_suppl): TPS4184-TPS4184,2023.

Alese OB, Wu C, Chapin WJ, Ulanja MB, Zheng-Lin B, Amankwah M, Eads J.: Update on Emerging Therapies for Advanced Colorectal Cancer Am Soc Clin Oncol Educ Book : 2023.

Chapin WJ, Reiss KA.: PARPis and Other Novel, Targeted Therapeutics in Pancreatic Adenocarcinoma Hematol Oncol Clin North Am : 2022.

Academic Contact Information

Perelman Center for Advanced Medicine
10 South Pavilion
3400 Civic Center Blvd
Philadelphia, PA 19104
Patient appointments: 800-789-7366

American Society of Clinical Oncology, National
European Society of Medical Oncology, International