About me
- Richard W. Vague Professor in Immunotherapy
- Professor of Pathology and Laboratory Medicine in Medicine (Hematology-Oncology)
Education and training
- Medical School: Baylor College of Medicine
- Residency: National Naval Med Center
- Fellowship: University of Washington Hospital and Clinics
My Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Qualifications and experience
- Medical Oncology, 1985
- Internal Medicine, 1982
- Alliance for Cancer Gene Therapy, National
- American Society Hematology, National
- American Society of Gene and Cell Therapy, International
- Clinical Immunology Society, National
- Danish Council for Strategic Research, International
- Duke Cancer Institute, Duke University (Member, Scientific Advisory Board), Local
- Gabrielle"s Angel Foundation for Cancer Research, National
- International Society for Biological Therapy of Cancer, National
- Memorial Sloan Kettering Cancer Center, Local
- Multiple Myeloma Research Foundation, National
- National Institutes of Health, National
- Stanford University Cancer Center, Local
- United Kingdom Quinquennial Review, International
- University of Minnesota, Local
- Abramson Cancer Center
Treatments and Conditions
My research
Porter David L, Levine Bruce L, Kalos Michael, Bagg Adam, June Carl H Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. , The New England journal of medicine, 365(8): 2011,725-33
Kalos Michael, Levine Bruce L, Porter David L, Katz Sharyn, Grupp Stephan A, Bagg Adam, June Carl H T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced Leukemia. , Science translational medicine, 3(95): 2011,95ra73
Rapoport Aaron P, Aqui Nicole A, Stadtmauer Edward A, Vogl Dan T, Fang Hong-Bin, Cai Ling, Janofsky Stephen, Chew Anne, Storek Jan, Akpek Gorgun, Badros Ashraf, Yanovich Saul, Tan Ming T, Veloso Elizabeth, Pasetti Marcela F, Cross Alan, Philip Sunita, Murphy Heather, Bhagat Rita, Zheng Zhaohui, Milliron Todd, Cotte Julio, Cannon Andrea, Levine Bruce L, Vonderheide Robert H, June Carl H Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma. , Blood, 117(3): 2011,788-97
Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, Liu O, Wang N, Lee G, Bartsevich VV, Lee YL, Guschin DY, Rupniewski I, Waite AJ, Carpenito C, Carroll RG, Orange JS, Urnov FD, Rebar EJ, Ando D, Gregory PD, Riley JL, Holmes MC, June CH. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. , Nat Biotechnol., 7: 2008,808-16
Paulos Chrystal M, Carpenito Carmine, Plesa Gabriela, Suhoski Megan M, Varela-Rohena Angel, Golovina Tatiana N, Carroll Richard G, Riley James L, June Carl H The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. , Science translational medicine, 2(55): 2010,55ra78
Gattinoni Luca, Lugli Enrico, Ji Yun, Pos Zoltan, Paulos Chrystal M, Quigley Máire F, Almeida Jorge R, Gostick Emma, Yu Zhiya, Carpenito Carmine, Wang Ena, Douek Daniel C, Price David A, June Carl H, Marincola Francesco M, Roederer Mario, Restifo Nicholas P A human memory T cell subset with stem cell-like properties. , Nature medicine, 17(10): 2011,1290-7
June CH, Blazar BR, Riley JL Engineering lymphocyte subsets: tools, trials and tribulations. , Nature Reviews Immunology, 9(10): 2009,704-16
Carpenito Carmine, Milone Michael C, Hassan Raffit, Simonet Jacqueline C, Lakhal Mehdi, Suhoski Megan M, Varela-Rohena Angel, Haines Kathleen M, Heitjan Daniel F, Albelda Steven M, Carroll Richard G, Riley James L, Pastan Ira, June Carl H Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. , Proceedings of the National Academy of Sciences of the United States of America, 106(9): 2009,3360-5
Riley James L, June Carl H, Blazar Bruce R Human T regulatory cell therapy: take a billion or so and call me in the morning. , Immunity, 30(5): 2009,656-65
Paulos CM, June CH Putting the brakes on BTLA in T cell-mediated cancer immunotherapy. , Journal of Clinical Investigation, 120(1): 2010,76-80