Description of Research Expertise

Scleroderma (Systemic Sclerosis) and related diseases clinical outcomes, therapeutic interventions and disease pathogenesis.

Selected Publications

Parperi K, Costi E, Philippou S, Hadi M, Derk CT: Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review Rheumatol Int 44 (11): 2371-79,2024.

GRASP study group: Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. ACR annual scientific meeting, Washington DC : 2024.

Ross L, Hansen D, Proudman S, Khanna D, Herrick AL, Stevens W, Australian Scleroderma Interest Group (ASIG), Canadian Scleroderma Research Group (CSRG), Baron M, Nikpour M, SCTC Activity Index Working Group: Development and initial validation of the novel Scleroderma Clinical Trials Consortium Activity Index Arthritis Rheumatol : 2024.

GRASP study group: Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis ACR annual scientific meeting, Washington DC : 2024.

GRASP study Group: TCR motifs identify unique clones in African Americans with systemic sclerosis ACR annual Scientific meeting, Washington DC : 2024.

Luo Y, Gordon J, Xu J, Kolstad KD, Chung L, Steen VD, Bernstein EJ, PHAROS Investigators: Prognostic significance of pericardial effusion in systemic sclerosis-associated pulmonary hypertension: analysis from the PHAROS registry Rheumatology kead368 : 2023.

Basyal B; Ullah W; Derk CT: Pericardial effusions and Cardiac Tamponade in hospitalized systemic sclerosis patients: analysis of the national inpatient sample BMC Rheumatol 7 (1): 34,2023.

Bean MB, Derk CT: Lower Extremity ulcers in patients with systemic sclerosis Open J Rheumatol Autoimmune Dis 12 (1): 35-45,2022.

Khanna D, Caldron P, Martin RW, Kafaja S, Spiera R, Shahouri S, Shah A, Hsu V, Ervin J, Simms R, Domsic RT, Steen V, Hummers LK, Derk C, Mayes M, Chatterjee S, Varga J, Kesten S, Draser JK, Furst DE: Adipose-derived regenerative cell transplantation for the treatment of hand dysfunction in systemic sclerosis: a randomized clinical trial Arthritis Rheumatol 74 (8): 1399-1408,2022.

GRASP study group: Genome-wide association study in African American systemic sclerosis patients identifies a novel target-transforming growth factor -beta 3 (TGF beta 3) American College of Rheumatology Annual Scientific meeting : 2022.

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Academic Contact Information

Division of Rheumatology
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
Phone: 215-662-2792
Patient appointments: 800-789-7366