Selected Publications
Young, AJ, Pantel, AR, Kiani, M, Doot, RK, Bagheri, S, Pryma, DA, Farwell, MD, Li, S, Lee, H, Schubert, E, Secreto, A, Zuckerman, S, Nayak, A, Choi, H, Carlin, S, DeMichele, A, Mankoff, DA, Zhou, R, Mach, RH, McDonald, ES.: "Kinetic Analysis and Metabolism of Poly-(Adenosine Diphosphate- Ribose) Polymerase-1–Targeted 18F-Fluorthanatrace PET in Breast Cancer" Journal of Nuclear Medicine : 2024.
McDonald, ES, Doot, RK, Pantel, AR, Farwell, MD, Mach, RH, Maxwell, KN, Mankoff, DA: Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial JAMA Oncology 6 (6): 921-923,2020.
McDonald ES, Oustimov A, Weinstein SP, Synnestvedt M, Schnall MD, Conant EF: Effectiveness of digital breast tomosynthesis compared with digital mammography: Outcomes analysis from 3 years of breast cancer screening JAMA Oncology 2 (6): 737-743,2016.
Edmonds, C, Weinstein, S, Bagheri, S, Zuckerman, S, Obrien, S, McDonald, ES, Schnall, M, Conant, E.: Abbreviated breast MRI for screening women with dense breasts at otherwise average risk: Comparison of performance on baseline versus sequential scans. American Journal of Roentgenology : 2024.
Chitalia, R., Pati, S., Bhalerao, M., Thakur, S., Jahani, N., Belenky, J. V., McDonald, E., Gibbs, J., Newitt, D., Hylton, N., Kontos, D., & Bakas, S.: Expert tumor annotations and radiomic features for the ISPY1/ACRIN 6657 trial data collection [Data set]. The Cancer Imaging Archive. (NCI) : 2022.
Lee, HS, Schwarz, SW, Schubert, EK, Chen, DL, Doot, RK, Makvandi, M, Lin, LL, McDonald, ES, Mankoff, DA, Mach, RH.: The Development of 18F Fluorthanatrace: A PET Radiotracer for Imaging Poly (ADP-Ribose) Polymerase-1 Radiol Imaging Cancer 4 (1): e210070. ,2022.
McDonald ES, Romanoff J, Rahbar H, Kitsch AE, Harvey SM, Whisenant JG, Yankeelov TE, Moy L, DeMartini WB, Dogan BE, Yang WT, Wang LC, Joe BN, Wilmes LJ, Hylton NM, Oh KY, Tudorica LA, Neal CH, Malyarenko DI, Comstock CE, Schnall MD, Chenevert TL, Partridge SC.: Mean Apparent Diffusion Coefficient Is a Sufficient Conventional Diffusion-weighted MRI Metric to Improve Breast MRI Diagnostic Performance: Results from the ECOG-ACRIN Cancer Research Group A6702 Diffusion Imaging Trial Radiology 298 (1): 60-70,2021.
McDonald ES, Pantel AR, Shah PD, Farwell MD, Clark AS, Doot RK, Pryma DA, Carlin SD.: In vivo visualization of PARP inhibitor pharmacodynamics JCI Insight 6 (8): e146592.,2022.
Zuckerman S and McDonald ES: Mammography Quality Standards Act (MQSA) and ACR Accreditation Programs CORE Requisites series in breast imaging : 2022.
Whisenant JG, Romanoff J, Rahbar H, Kitsch AE, Harvey SM, Moy L, DeMartini WB, Dogan BE, Yang WT, Wang LC, Joe BN, Wilmes LJ, Hylton NM, Oh KY, Tudorica LA, Neal CH, Malyarenko DI, McDonald ES, Comstock CE, Yankeelov TE, Chenevert TL, Partridge SC.: Factors Affecting Image Quality and Lesion Evaluability in Breast Diffusion-weighted MRI: Observations from the ECOG-ACRIN Cancer Research Group Multisite Trial (A6702) J Breast Imaging 3 : 44-56,2020.
Elmi A, Conant EF, Kozlov A, Young AJ, Long Q, Doot RK, McDonald ES: Preoperative breast MR imaging in newly diagnosed breast cancer: Comparison of outcomes based on mammographic modality, breast density and breast parenchymal enhancement. Clin Imaging 70 : 18-24,2021.
Li W, Newitt D, Gibbs J, Wilmes L, Jones E, Arasu V, Strand F, Onishi, N, Kornack J, Joe BN, Price E, Ojeda-Fournier Haydee, Zamora KW, Woodard SA, Wolverton D, Brandt, KR, McDonald ES, Rosen m, Kontos D, Rahbar H, Crane E, Pulin S, Niell B, Drukteinis J, Newell MS, Cohen M, Giurescu M, Berman E, Lehman C, Partridge, SC, Fitzpatrick K, Borders M, Yang, W, Basak D, Goudreau S, Berry D, DeMichele, A, Yau C, Hylton NM, Esserman, L.: Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL NPJ Breast Cancer 6 (1): 63,2020 .
Susan P. Weinstein, MD, Mitchell D. Schnall, MD, PhD, Claire M. Cirelli, Arijitt Borthakur, MBA, PhD, Elizabeth McDonald, MD, PhD, Emily F. Conant, MD: Abbreviated Breast MR for Supplemental Screening of Women with Dense Breasts and Average Risk Journal of Clinical Oncology 38 (33): 3874-3882,2020.
McDonald, ES, Doot, RK, Young, AJ, Shubert, ES, Tchou, J, Pyrma, DA, Farwell, MD, Nayak, A, Ziober, A, Feldman, MD, DeMichele, A, Clark, AS, Shah, PD, Lee, H, Carlin, SD, Mach, RH, Mankoff, DA: Breast Cancer 18F-ISO-1 Uptake as a Marker of Proliferation Status
Journal of Nuclear Medicine 61 (5): 665-670,2020.
Elmi A, McDonald ES, Mankoff D.: Imaging Tumor Proliferation in Breast Cancer: Current Update on Predictive Imaging Biomarkers. PET Clin 13 (3): 445-457,2018.
Conant, EF, Zuckerman, S, McDonald, ES, Weinstein, SP, Korhonen, K, Synnestvedt, M, Schnall, M, Hubbard, RA: Five Consecutive Years of Screening with Digital Breast Tomosynthesis:
Outcomes by Screening Year and Round
Radiology 295 (2): 285-293,2020.
Chitalia R, Rowland J, McDonald ES, Pantalone L, Cohen EA, Gastounioti A, Feldman M, Schnall M, Conant E, Kontos D.: Imaging phenotypes of breast cancer heterogeneity in pre-operative breast Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) scans predict 10-year recurrence Clinical Cancer Research 26 (4): 862-869,2020.
Rahbar H, Zhang Z, Chenevert TL, Romanoff J, Kitsch AE, Hanna LG, Harvey SM, Moy L, DeMartini WB, Dogan B, Yang WT, Wang LC, Joe BN, Oh KY, Neal CH, McDonald ES, Schnall MD, Lehman CD, Comstock CE, Partridge SC: Utility of Diffusion-weighted Imaging to Decrease Unnecessary Biopsies Prompted by Breast MRI: A Trial of the ECOG-ACRIN Cancer Research Group (A6702) Clinical Cancer Research 25 (6): 1756-1765,2019.
Chong A, Weinstein SP, McDonald ES, Conant EF: Digital Breast Tomosynthesis: Concepts and Clinical Practice Radiology 292 (1): 1-14,2019.
Le TT, McDonald ES, Isaac G, Rosen M, Dougherty L: Effect of Contrast Dose on Diagnostic Performance in DCE-MR Breast Imaging Journal of Applied Clinical Medical Physics 21 (11): 188-194,2020.
Korhonen KE, Conant EF, Cohen EA, Synnestvedt M, McDonald ES, Weinstein SP: Breast Cancer Conspicuity on Simultaneously Acquired Digital Mammographic Images versus Digital Breast Tomosynthesis Images Radiology 292 (1): 69-76,2019.
Mirzabeigi MN, Rhemtulla IA, Mcdonald ES, Sataloff DM, Kovach SJ, Wu LC, Serletti JM, Kanchwala S.: Locoregional Cancer Recurrence after Breast Reconstruction: Detection, Management, and Secondary Reconstructive Strategies Plastic and Reconstructive Surgery 143 (5): 1322-1330,2019.
Derakhshan JJ, McDonald ES, Siegelman ES, Schnall MD, Wehrli FW: Characterizing and eliminating errors in enhancement and subtraction artifacts in dynamic contrast-enhanced breast MRI: Chemical shift artifact of the third kind Magnetic Resonance in Medicine 79 (4): 2277-2289,2018.
McDonald ES, Ulaner GA.: Uses and Opportunities for Molecular Imaging in Patients with Breast Cancer. PET Clin. 2018 Jul;13(3):xi-xii. 13 (3): xi-xii,2018.
Hsu JC, Naha PC, Lau KC, Chhour P, Hastings R, Moon BF, Stein JM, Witschey WRT, McDonald ES, Maidment ADA, Cormode DP: An all-in-one nanoparticle (AION) contrast agent for breast cancer screening with DEM-CT-MRI-NIRF imaging Nanoscale 10 (36): 17236-17248,2018.
So A, De La Cruz LM, Williams AD, Bahng J, Liao G, McDonald ES, Fisher CS, Czerniecki BJ, Sataloff D, Tchou J: The impact of preoperative magnetic resonance imaging and lumpectomy cavity shavings on re-excision rate in pure ductal carcinoma in situ-A single institution's experience Journal of Surgical Oncology 117 (4): 558-566,2018.
Zuckerman SP, Maidment ADA, Weinstein SP, McDonald ES, Conant EF: Imaging with synthesized 2D mammography: differences, advantages, and pitfalls compared with digital mammography American Journal of Roentgenology 209 (1): 222-229,2017.
McDonald ES, McCarthy AM, Weinstein SP, Schnall MD, Conant EF: BI-RADS category 3 comparison: probably benign category after recall from screening before and after implementation of digital breast tomosynthesis Radiology 285 (3): 778-787,2017.
McDonald ES, Mankoff D, Makvandi M, Chu W, Chu Y, Mach RH, Zeng C: Sigma-2 ligands and PARP inhibitors synergistically trigger cell death cancer cells Biochemical and Biophysical Research Communications 486 (3): 788-795,2017.
Zeng C, McDonald ES, Mach RH: Molecular probes for imaging the sigma-2 receptor: In vitro and in vivo imaging studies Handbook of Experimental Pharmacology 244 : 309-330,2017.
Conant EF, Keller BM, Pantalone L, Gastounioti A, McDonald ES, Kontos D: Agreement between breast percentage density estimations from standard-dose versus synthetic digital mammograms: Results from a large screening cohort using automated measures Radiology 283 (3): 673-680,2017.
Cruz, L, McDonald, ES, Mick, R, Czerneicki, B: Anti-HER2 Th1 Response is Superior to Breast MRI in Response to Neoadjuvant Chemotherapy in Patients with HER2 Positive Breast Cancer Annals of Surgical Oncology 24 (4): 1057-1063,2017.
Chudgar, AV, Conant, EF, Weinstein, SP, Keller, BM, Synnestvedt, M, Yamartino, P, McDonald, ES: Assessment of disease extent on contrast-enhanced MRI in breast cancer detected at digital breast tomosynthesis versus digital mammography alone Clinical Radiology 72 (7): 573-579,2017.
Mitsumori LM, McDonald ES, Neligan PC, Maki JH: Peripheral Magnetic Resonance Lymphangiography: Techniques and Applications Techniques in Vascular and Interventional Radiology 19 (4): 262-272,2016.
Korhonen KE, Weinstein SP, McDonald ES, Conant EF: Strategies to increase cancer detection: Review of true-positive and false-negative results at digital breast tomosynthesis screening Radiographics 36 (7): 1954-1965,2016.
Naha PC, Lau KC, Hsu JC, Hajfathalian M, Mian S, Chhour P, Uppuluri L, McDonald ES, Maidment AD, Cormode DP: Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography Nanoscale 8 (28): 13740-13754,2016.
Makvandi, M, Xu, K, Lieberman, BP, Anderson, R, Effron, SS, Winters, H, Zeng, C, McDonald, ES, Pryma, DA, Greenberg, RA, Mach, RH: A radiotracer strategy to quantify PARP-1 expression in vivo provides a biomarker that can enable patient selection for PARP inhibitor therapy Cancer Research 76 (15): 4516-4524,2016.
Zuckerman S,Conant EF,Keller B,Weinstein S,McDonald ES.: Implementation of synthesized 2D mammography in a population-based digital breast tomosynthesis screening program Radiology 28 (1): 730-736,2016.
McDonald ES, Mankoff DA, Mach RH: Novel strategies for breast cancer imaging: new imaging agents to guide treatment Journal of Nuclear Medicine 57 : 69S-74S,2016.
McDonald ES, Hammersley JA, Chou SS, Rahbar H, Scheel JR, Lee CI, Liu CL, Lehman CD, Partridge SC: Performance of DWI as a Rapid Unenhanced Technique for Detecting Mammographically Occult Breast Cancer in Elevated-Risk Women with Dense Breasts American Journal of Roentgenology 207 (1): 205-216,2016.
Mirzabeigi MN, McDonald ES, Chu MW, Fischer JP, Basta M, Kovach S, Wu LC, Serletti J, Kanchwala S: Operative management of locoregional cancer recurrence following post-mastectomy breast reconstruction-indications and outcomes American Society for Reconstructive Microsurgery : 2016.
Chen L, Ray S, Keller BM, Pertuz S, McDonald ES, Conant EF, Kontos D: The Impact of acquisition dose on quantitative breast density estimation with digital mammography: Results from ACRIN PA 4006 Radiology 280 (3): 693-700,2016.
McDonald ES, Clark A, Tchou J, Zhang, P, Freedman, G.: Clinical diagnosis and management of breast cancer Journal of Nuclear Medicine 57 (Suppl 1): 9S-16S,2016.
Pertuz S, McDonald ES, Weinstein SP, Conant EC, Kontos D: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging Radiology 279 (1): 65-74,2016.
Rahbar, H, McDonald, ES, Lee, JM, Partridge, SC, Lee, CI.: How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis? Academic Radiology 23 (6): 768-773,2016.
Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA, Mach RH: The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer Biochemical and Biophysical Research Communications 467 (4): 1070-1075,2015.
Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH: MR Lymphangiography: How I do it Journal of Magnetic Resonance Imaging 42 (6): 1465-1477,2015.
McDonald ES, McCarthy AM, Akhtar A, Synnestvedt A, Schnall M, Conant EF: Baseline screening mammography: Performance of full field digital versus digital breast tomosynthesis American Journal of Roentgenology 205 (5): 1143-1148,2015.
McDonald ES, Conant EF: Breast MRI 4th Edition, Radiology Secrets Plus Radiology Secrets : 2016.
Clark AS, McDonald E, Lynch MC, Mankoff D: Using nuclear medicine imaging in clinical practice: update on PET to guide treatment of patients with metastatic breast cancer Oncology 28 (5): 424-430,2014.
Doot RK, McDonald ES, Mankoff DA: Role of PET quantitation in the monitoring of cancer response to treatment: review of approaches and human clinical trials Clinical and Translational Imaging 2 (4): 295-303,2014.
McDonald ES, Schopp JG, Peacock S, DeMartini WB, Rahbar H, Lehman CD, Partridge SC: Diffusion-weighted MRI: association between patient characteristics and apparent diffusion coefficients of normal breast fibroglandular tissue at 3 T American Journal of Roentgenology 202 (5): W496-502,2014.
Partridge SC, McDonald ES: Diffusion weighted magnetic resonance imaging of the breast: protocol optimization, interpretation, and clinical applications Magnetic Resonance Imaging Clinics of North America 21 (3): 601-624,2013.
Academic Contact Information
Hospital of University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street
Philadelphia,
PA
19104