Penn Medicine Provider

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  • Professor of Orthopaedic Surgery

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Ji X, Seeley R, Li K, Song F, Liao X, Song C, Angelozzi M, Valeri A, Marmo T, Lee WC, Shi Y, Long F Genetic activation of glycolysis in osteoblasts preserves bone mass in type I diabetes , Cell Chem Biol.: 2023


Song F, Lee WD, Marmo T, Ji X, Song C, Liao X, Seeley R, Yao L, Liu H, Long F Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice , Elife: 2023


Li K, Ji X, Seeley R, Lee WC, Shi Y, Song F, Liao X, Song C, Huang X, Rux D, Cao J, Luo X, Anderson SM, Huang W, Long F Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis , FASEB J.: 2022


Lee WC, Ji X, Nissim I, Long F. Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts , Cell Rep, 32: 2020,108108


Seung-Yon Lee and Fanxin Long Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation. , JCI, 128(12): 2018,5573


Lee SY, Abel ED, Long F Glucose metabolism induced by Bmp signaling is essential for murine skeletal development , Nat Commun., 9(1): 2018,4831


Yu Shi, Guangxu He, Wen-Chih Lee, Jenny A. McKenzie, Matthew J. Silva, Fanxin Long Gli1 identifies osteogenic progenitors for bone formation and fracture repair. , Nat Commun., 8(1): 2017,2043


Shi Y, Chen J, Karner CM and Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. , PNAS, 112(15): 2015,4678-4683


Chen J. and Long F. mTORC1 signaling critically controls mammalian skeletal growth through stimulation of protein synthesis. , Development , 141(14): 2014,2848-2854


Emel Esen, Jianquan Chen, Courtney M. Karner, Adewole L. Okunade, Bruce W. Patterson, Fanxin Long. WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. , Cell Metab. , 17(5): 2013,745-755


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