About me
- Professor of Orthopaedic Surgery
My Locations
Qualifications and experience
- American Society of Bone and Mineral Diseases, International
- Endocrine Society, International
- Membership: Orthopaedic Research Society, International
Treatments and Conditions
My research
Ji X, Seeley R, Li K, Song F, Liao X, Song C, Angelozzi M, Valeri A, Marmo T, Lee WC, Shi Y, Long F Genetic activation of glycolysis in osteoblasts preserves bone mass in type I diabetes , Cell Chem Biol.: 2023
Song F, Lee WD, Marmo T, Ji X, Song C, Liao X, Seeley R, Yao L, Liu H, Long F Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice , Elife: 2023
Li K, Ji X, Seeley R, Lee WC, Shi Y, Song F, Liao X, Song C, Huang X, Rux D, Cao J, Luo X, Anderson SM, Huang W, Long F Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis , FASEB J.: 2022
Lee WC, Ji X, Nissim I, Long F. Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts , Cell Rep, 32: 2020,108108
Seung-Yon Lee and Fanxin Long Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation. , JCI, 128(12): 2018,5573
Lee SY, Abel ED, Long F Glucose metabolism induced by Bmp signaling is essential for murine skeletal development , Nat Commun., 9(1): 2018,4831
Yu Shi, Guangxu He, Wen-Chih Lee, Jenny A. McKenzie, Matthew J. Silva, Fanxin Long Gli1 identifies osteogenic progenitors for bone formation and fracture repair. , Nat Commun., 8(1): 2017,2043
Shi Y, Chen J, Karner CM and Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. , PNAS, 112(15): 2015,4678-4683
Chen J. and Long F. mTORC1 signaling critically controls mammalian skeletal growth through stimulation of protein synthesis. , Development , 141(14): 2014,2848-2854
Emel Esen, Jianquan Chen, Courtney M. Karner, Adewole L. Okunade, Bruce W. Patterson, Fanxin Long. WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. , Cell Metab. , 17(5): 2013,745-755