About me
- Professor of Orthopaedic Surgery
My Locations
Qualifications and experience
- Abramson Cancer Center of the University of Pennsylvania, Local
- American Society for Bone and Mineral Research, National
- Association of Osteobiology, International
- Bone Marrow Adiposity Society, International
- Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Local
- Center for Advancement of Science in Space, National
- DOD Medical Research Program (PRMRP) Arthritis-1 (ART-1) Panel, National
- IACUC Committee, Local
- Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Local
- Institute for Regeneration Medicine, University of Pennsylvania, Local
- Institute on Aging, Local
- International Chinese Musculoskeletal Research Society, International
- International Society of Bone Morphometry, International
- National Society for Histotechnology, National
- NIH SBDD (Skeletal Biology Development & Disease) Study Section, National
- NIH Special Emphasis Panel, National
- Orthopaedic Research Club, University of Pennsylvania, Philadelphia, PA, Local
- Orthopaedic Research Society, National
- Penn Center for Musculoskeletal Disorders, Local
- Penn Center for Musculoskeletal Disorders, University of Pennsylvania, Local
Treatments and Conditions
My research
Tang, S. #, Yao, L. #, Ruan, J., Kang, J., Cao, Y., Nie, X., Lan, W., Zhu, Z., Han, W., Liu, Y., Tian, J., Seale, P., Qin, L. *, Ding, C*. #: these authors contributed equally to this work. *: co-corresponding authors. Single-cell atlas of human infrapatellar fat pad and synovium unravels mechanisms of osteoarthritis-induced joint pathology. , Sci Transl Med. , 16: 2024,eadf4590
Chowdhury, P., Velalopoulou A., Verginadis, I., Morcos, G., Loo, P., Kim, M., Motlagh, S.Z.O., Shoniyozov, Kl, Diffenderfer, E., Ocampo, E., Putt, M., Assenmacher, C., Radaellli, E., Lu, J., Qin, L., Liu, H., Leli, N.M., Girdhani, S., Denef, N., Sappen, F., Cengel, K., Busch, T., Metz, J., Dong, L., Lin, A., and Koumenis, C. Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer. , Mol. Cancer Ther., 23: 2024,877-889
Bandyopadhyay, S., Duffy, M., Ahn, K.J., Pang, M., Smith, D., Duncan, G., Sussman, J., Zhang, I., Huang, J., Lin, Y., Xiong, B., Imtiaz, T., Chen, C., Thadi, A., Chen, C., Xu, J., Reichart, M., Pillai, V., Snaith, O., Oldridge, D., Bhattacharyya, S., Maillard, I., Carroll, M., Nelson, C., Qin, L.*, and Tan, K*. *: co-corresponding authors. Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic Imaging. , Cell, 187: 2024,3120-3140
Chen, K., Tian, Z., Wang, H., Qin, L., Enomoto-Iwamoto, M., and Zhang, Y. Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. , Am. J. Phys. Med. , 104: 2024,45-50
Zhang, C., Zhong, L., Lau, Y.K., Wu, M., Schaer, T.P., Mauck, R.L., Malhotra, N.R., Qin, L. and Smith, L.J. Single cell RNA sequencing reveals emergent Notochord-derived cell subpopulations in the postnatal nucleus pulposus. , FASEB J. , 38: 2024,e23363
Collins, J.M., Lang, A., Parisi, C., Moharrer, Y., Nijsure, M.P., Kim, J.H., Szeto, G.L., Qin, L., Gottardi, R.L., Dyment, N.A., Nowlan, N.C., and Boerckel, J.D. YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development. , Dev. Cell. , 59: 2024,211-227
Li, J.#, Gui, T.#, Yao, L., Guo, H., Lin, Y., Lu, J., Fang, J., Duffy, M., Zgonis, M., Mauck, R., Dyment, N., Zhang, Y., Scanzello, C., Seale, P., and Qin, L. #: these authors contributed equally to this work. Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. , J Bone Miner Res. , 39: 2024,161-176
Tian, Z., Shofer F.S., Fan, M., Sandroni, A.Z., Yao, L., Han, L., Qin, L., Enomoto-Iwamoto, M., and Zhang, Y. ADAM8 inactivation retards intervertebral disc degeneration in mice. , Genes Dis. , 11: 2024,101059
Bautista, C.A., Srikumar, A., Tichy, E.D., Qian, G., Jiang, J.X., Qin, L., Mourkioti, F., Dyment, N.A. CD206+ tendon resident macrophages and their crosstalk with fibroblasts and the ECM during tendon growth and maturation. , Front Physiol. , 14: 2023,1122348
Dillard, L.J., Rosenow, W., Calabrese, G., Mesner, L.D., Al-Barghouthi, B.M., Abood, A., Farber, E.A., Onengut-Gumuscu, S., Tommasini, S.M., Horowitz, M.A., Rosen, C.J., Yao, L., Qin, L., and Farber, C.R. Single-cell transcriptomics of bone marrow stromal cells in diversity outbred mice: a model for population-level scRNA-Seq studies. , J Bone Miner Res. , 38: 2023,1350-1363