Matthew J. O'Connor, MD

Pediatric Cardiology

Sees newborns through age 18

Matthew J. O'Connor, MD

Pediatric Cardiology

Sees newborns through age 18

Professor of Clinical Pediatrics (Cardiology)
Dr. O'Connor is an independent physician who is not employed by Penn Medicine Lancaster General Health.

Call 717-544-0375 Request Appointment

Alagille Syndrome
Anomalies of the Aorta
Anomalous Coronary Artery
Anomalous Pulmonary Venous Return
Aortic Valve Disorders
Aortopulmonary Window
Arrhythmia (Irregular Heartbeat)
Athlete's Heart
Atrial Septal Defect (ASD)
Atrioventricular Canal Defect
Atrioventricular Septal Defect
Bacterial Endocarditis
Barth Syndrome
Bicuspid Aortic Valve Disease
Brugada Syndrome
Cardiomyopathy (Cardiomyopathies)
Cardio-Oncology
Cardiorenal Syndrome (CRS)
Common Aortopulmonary Trunk
Congenital Anomaly of the Aortic Arch
Congenital Anomaly of the Coronary Artery
Congenital Heart Disease
Congenital Infundibular Stenosis
Congenital Insufficiency of the Aortic Valve
Congenital Mitral Valve Regurgitation
Congenital Pulmonary Valve Atresia
Congenital Stenosis of the Aortic Valve
Congenital Stenosis of the Mitral Valve
Congenital Stenosis of the Pulmonary Valve
Congenital Subaortic Stenosis
Congenital Tricuspid Stenosis
Congenitally Corrected Transposition of the Great Arteries
Congestive Heart Failure (CHF)
Constrictive Pericarditis
Coronary Artery Anomaly
Coronary Artery Fistula
Cyanotic Heart Disease
Dextrocardia
Dilated Cardiomyopathy
Double Aortic Arch
Double Outlet Right Ventricle
Ebstein Anomaly
Ehlers-Danlos Syndrome
Eisenmenger Syndrome
Endocardial Cushion Defect
Familial Arrhythmias
Familial Cardiomyopathy
Familial Dyslipidemia
Fetal Arrhythmia
Fetal Cardiology
Fetal Cardiomyopathy
Genetic Cardiomyopathy
Genetic Heart Disease
Heart Block
Heart Murmur
Heart Tumor (Cardiac Tumor)
Hemitruncus
Hypertension (High Blood Pressure)
Hypertrophic Cardiomyopathy
Hypoplastic Left Heart Syndrome
Idiopathic Hypertrophic Subaortic Stenosis
Inherited Cardiac Arrhythmia
Kabuki Syndrome
Kawasaki Disease
Loeys-Dietz Syndrome
Long QT Syndrome
Marfan Syndrome
Mitral Stenosis
MTHFR Mutation
Partial Anomalous Pulmonary Venous Return
Patent Ductus Arteriosus
Patent Foramen Ovale (PFO)
Peripheral Pulmonary Stenosis
Persistent Ostium Primum
Pulmonary Artery Coarctation and Atresia
Pulmonary Artery Stenosis
Pulmonary Hypertension
Pulmonary Valve Disorders
Pulmonary Valve Insufficiency
Pulmonary Valve Stenosis (PVS)
Pulmonary Vein Stenosis
Pulmonary Veno Occlusive Disease
Restrictive Cardiomyopathy
Septal Defect
Subaortic Stenosis
Supravalvular Aortic Stenosis
Syncope
Tetralogy of Fallot
Transposition of the Great Vessels
Tricuspid Atresia
Truncus Arteriosus
Tufted Angioma
Twin Reversed Arterial Perfusion
Velo-Cardio-Facial Syndrome
Ventricular Septal Defect (VSD)
Viral Cardiomyopathy
Wolff-Parkinson-White Syndrome (WPW)

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Board Certification

Pediatrics, 2007
Pediatrics/Cardiology (AMA)

Education and Training

Medical School: University of Virginia
Residency: University of Virginia; University of Virginia Children's Hospital
Fellowship: Children's Hospital of Philadelphia

Primary Location

CHOP Specialty Care, Lancaster

Suite 300
2104 Harrisburg Pike
Lancaster, PA 17601

Map Call 717-544-0375

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Penn Medicine Hospital Privileges

Chester County Hospital: Has privileges to treat patients in the hospital.
Lancaster General Hospital: On the medical staff, but does not have privileges to treat patients in the hospital.

Selected Publications

Bell S, Berger J, Boyle C, Edelson JB, Edwards JJ, Ha L, Lin KY, Maeda K, Rossano JW, Wittlieb-Weber CA, White R, O'Connor MJ: Characteristics and outcomes of children determined to be noncandidates for heart transplant JHLT Open 4 : 2024.

Edelson J, Raskin A, Absi M, Bearl D, Bonilla Ramirez C, Do N, Knoll C, Lorts A, Martinez H, Maeda K, O'Connor M, Rosenthal D, Shezad M, Wisotzkey B, Niebler R: Collective Five Year ACTION VAD Registry Experience International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Mejia EJ, Koehl D, Cantor R, Kirklin J, Morales D, Perry T, Maeda K, Lin K, Edelson J, O'Connor M, Wittlieb-Weber C, Edwards J, Rossano J: Long Term Ventricular Assist Devices in Children International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Edelson J, Huang J, Wang Z, Lefkowitz D, O'Connor M, White R, Ha L, Wittlieb-Weber C, Rossano J, Lin K, Lane-Fall M, O'Byrne M: Identifying the Environmental Determinants of Health-Related Quality of Life in Children After Heart Transplant International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Moon J, Sood V, Lorts A, Shezad M, O'Connor M: The Outcomes of Temporary Mechanical Circulatory Support Using Paracorporeal Continuous Flow Pump in Children; A Multicenter Study Using ACTION Learning Network International Society for Heart and Lung Transplantation Annual Meeting : 2024.

O'Connor MJ, Zhang Z, Bennett L, Vu C, Ahmed H, Edwards J, Lin K, Maeda K, Rossano J, Edelson J: Panel Reactive Antibody, Crossmatch Status, and Outcomes in Pediatric Heart Transplant Recipients with Congenital Heart Disease: An Analysis of the United Network for Organ Sharing Database International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Townsend M, O'Connor MJ, Spinner JA, Amdani S, Conway J: Practice Variation in Anticoagulation Management of Outpatient Pediatric Cardiomyopathy Patients: Survey of ACTION Providers International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Chaudhary AA, Kramer E, Weber D, Ahmed H, O'Connor MJ, Edelson JB, Edwards JJ, Lin KY, Rossano JW, Wittlieb-Weber CA, Berger J: Initial Experience of Sodium-Glucose Cotransporter 2 Inhibitors in Adolescents with Heart Failure Due to Muscular Dystrophy International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Olson EM, Lin KY, Edelson JB, Rossano JW, Wittlieb-Weber CA, Edwards JJ, Maeda K, Restaino K, Boyle C Ha L, O'Connor MJ: Extensive Metastatic Calcification After Heart Transplant International Society for Heart and Lung Transplantation : 2024.

Masood I, Wang L, Roberts AL, Stanley H, Rossano J, O'Connor M, Lin K, Wittlieb-Weber C, Ahmed H, Edwards J, Tam V, Edelson J: Impact of Neighborhood Factors on Exercise Capacity in Children with Hypertrophic Cardiomyopathy International Society for Heart and Lung Transplantation Annual Meeting : 2024.

Academic Contact Information

Children's Hospital of Philadelphia
Division of Cardiology
3401 Civic Center Blvd
Philadelphia, PA 19104
Phone: 267-426-5700
Patient appointments: 800-789-7366

ACTION-Advanced Cardiac Therapies Improving Outcomes Network, National
American Heart Association, National
International Society for Heart and Lung Transplantation, International
United Network for Organ Sharing, National