Description of Research Expertise

Dr. Carey is a surgeon-scientist engaged in research aimed at improving the diagnosis and treatment of head and neck cancer. He runs a cancer neuroscience lab that investigates how head and neck cancer cells interact with the local tumor environment. His lab is specifically focused on G-protein coupled receptors including taste receptors and how the involved signaling pathways can regulate important cellular processes in head and neck cancer. The goal is to leverage taste receptors as biomarkers or therapeutic targets for treating malignancies. His group is actively translating their basic science findings from bench to bedside through clinical trials on therapies developed in the lab.

Additional information about the Carey lab is available at: https://www.med.upenn.edu/carey-lab/.

Selected Publications

Tapescu I, Kohler A, Sangal NR, Brant JA, Brody RM, Cao T, Carey RM: Thyroid Malignancies With Thymic Differentiation: Outcomes of Rare SETTLE and CASTLE Tumors Head Neck : 2024.

Huang L, Patel AM, Haleem A, Brant JA, Maxwell R, Brody RM, Carey RM: Missed Adjuvant Therapy in Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma Laryngoscope : 2024.

Patel AM, Haleem A, Revercomb L, Brant JA, Kohanski MA, Adappa ND, Palmer JN, Douglas JE, Carey RM: Surgical resection and overall survival in cT4b sinonasal non-squamous cell carcinoma Laryngoscope Investigative Otolaryngology : 2024.

Kaki PC, Patel AM, Maxwell R, Brant JA, Brody RM, Adappa ND, Palmer JN, Douglas JE, Carey RM: Choice of adjuvant radiotherapy facility in sinonasal squamous cell carcinoma Laryngoscope : 2024.

Kaki PC, Patel AM, Revercomb L, Maxwell R, Sun LL, Brant JA, Brody RM, Cannady SB, Carey RM.: Impact of Facility Volume on Overall Survival in Patients with Head and Neck Cancer Undergoing Palliative Treatment American Journal of Hospice and Palliative Medicine : 2024.

Patel AM, Haleem A, Revercomb L, Brant JA, Rajasekaran K, Sun LL, Brody RM, Carey RM: Primary site surgical resection in cM1 oral cavity squamous cell carcinoma. Laryngoscope Investigative Otolaryngology : 2024.

Miller ZA, Muthuswami S, Mueller A, Ma RZ, Sywanycz SM, Naik A, Brody RM, Diab A, Carey RM, Lee RJ: GLUT1 inhibitor BAY-876 induces apoptosis and enhances anti-cancer effects of bitter receptor agonists in head and neck squamous carcinoma cells Cell Death and Discovery : 2024.

Patel AM, Haleem A, Choudhry HS, Brody RM, Brant JA, Carey RM: Elective neck dissection in cT1-4 N0M0 head and neck basaloid carcinoma Otolaryngology-Head and Neck Surgery : 2024.

Patel AM, Haleem A, Choudhry HS, Brant JA, Brody RM, Carey RM: Surgical Resection Improves Overall Survival in cT4b Major Salivary Gland Cancer Otolaryngology-Head and Neck Surgery : 2024.

Patel AM, Haleem A, Maxwell R, Lukens JN, Lin A, Brody RM, Brant JA, Carey RM: Choice of adjuvant radiotherapy facility in major salivary gland cancer Laryngoscope : 2024.

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Academic Contact Information

Department of Otolaryngology-Head & Neck Surgery
University of Pennsylvania
3400 Spruce Street, 5 Ravdin
Philadelphia, PA 19104
Patient appointments: 800-789-7366