Description of Research Expertise

Dr. Nazarian is a clinical and translational investigator in the field of cardiac electrophysiology and is particularly interested in integration of advanced imaging modalities for optimization of procedural success for ablation of complex ventricular arrhythmia in structural heart disease. In addition to his medical expertise, Dr. Nazarian has a Ph.D. degree in Clinical Epidemiology from the Johns Hopkins Bloomberg School of Public Health. He has published extensively on the anatomy of the ventricular arrhythmia substrate. In his arrhythmia imaging laboratory, he oversees a team of individuals dedicated to facilitating atrial and ventricular arrhythmia research and clinical care within an academic medical center environment. Dr. Nazarian has been and continues to serve as the principal investigator for several grants from the National Institutes of Health to characterize the substrate for malignant arrhythmia.

Selected Publications

Toloubidokhti M, Gharbia OA, Parkosa A, Trayanova N, Hadjis A, Tung R, Nazarian S, Sapp JL, Wang L.: Understanding the Utility of Endocardial Electrocardiographic Imaging in Epi-Endocardial Mapping of 3D Reentrant Circuits medRxiv : 2024.

Liao TE, Xu L, Khoshknab MP, Peters CJ, Callans DJ, Marchlinski FE, Schaller RD, Frankel DS, Luebbert JJ, Guandalini GS, Nazarian S.: Techniques and outcomes of atrial fibrillation ablation in patients with persistent left superior vena cava J Cardiovasc Electrophysiol : 2024.

Yogasundaram H, Petzl AM, Raad M, Chaumont C, Guandalini GS, Kumareswaran R, Hyman MC, Schaller RD, Supple GE, Garcia FC, Nazarian S, Lin D, Riley MP, Dixit S, Callans DJ, Marchlinski FE, Frankel DS.: Combined catheter ablation of atrial fibrillation and premature ventricular complexes Heart Rhythm : 2024.

Khoshknab M, Zghaib T, Xu L, Markman T, Mavroudis C, Desjardins B, Nazarian S.: Noninvasive Visualization of the Atrioventricular Conduction System Using Cardiac Computed Tomography JAMA Cardiol 9 : 909-913,2024.

Markman TM, Xu L, Zahid S, Patel D, Marchlinski FE, Callans D, Nazarian S.: Augmentation of Atrial Conduction Velocity With Pharmacological and Direct Electrical Sympathetic Stimulation JACC Clin Electrophysiol : 2024.

Yogasundaram H, Papireddy MR, Nazarian S, Guandalini GS, Markman TM, Schaller RD, Riley MP, Lin D, Dixit S, D'Souza B, Kumareswaran R, Callans DJ, Frankel DS, Garcia FC, Zado E, Deo R, Epstein AE, Supple GE, Marchlinski FE, Hyman MC.: Long-term risk of right coronary artery injury after catheter ablation of cavotricuspid isthmus-dependent flutter Heart Rhythm : 2024.

Markman TM, Lin D, Nazarian S, van Niekerk CJ, Mirwais M, Garg L, Bode W, Smietana J, Sugrue A, Patel NA, Patel D, Ha B, Hyman MC, Riley M, Callans DJ, Deo R, Yang R, Schaller RD, Kumareswaran R, Guandalini GS, Epstein AE, Marchlinski FE, Frankel DS.: Intraoperative pectoral nerve blocks during cardiac implantable electronic device procedures Heart Rhythm : 2024.

Wasiak M, DePietro D, Chaumont C, Oraii A, Schaller R, Supple G, Nazarian S, Garcia F, Trerotola S, Soulen MC, Marchlinski FE, Frankel DS.: Transhepatic approach for catheter ablation of atrial fibrillation in patients with interrupted inferior vena cava Heart Rhythm : 2024.

Alderete J, Fernández-Armenta J, Zucchelli G, Sommer P, Nazarian S, Falasconi G, Soto-Iglesias D, Silva E, Mazzocchetti L, Bergau L, Khoshknab M, Penela D, Berruezo A.: The Ablate-by-LAWT multicentre prospective study: Personalized paroxysmal atrial fibrillation ablation with ablation index adapted to local left atrial wall thickness J Interv Card Electrophysiol : 2024.

Keane S, Patel D, Otto B, Englander L, Kumareswaran R, Lin D, Riley MP, Nazarian S, Marchlinski FE, Markman TM.: Incidental ablation of ganglionated plexus during atrial fibrillation ablation J Interv Card Electrophysiol : 2024.

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Academic Contact Information

Hospital of the University of Pennsylvania
Cardiac Electrophysiology, 9 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Phone: 215-615-5220
Patient appointments: 800-789-7366