Description of Research Expertise
Sarah Schrauben, MD, MSCE is Assistant Professor of Medicine and Epidemiology in the Division of Renal, Electrolyte, and Hypertension, and Department of Biostatistics, Epidemiology, and Informatics at the Perelman School of Medicine and a Senior Scholar in the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania. Her research focuses on the impact of health behaviors and modifiable risk factors in the development and management of chronic kidney disease (CKD) and its complications, as well as addressing implementation gaps of evidence-based care in CKD. She has contributed to the growing evidence base that seeks to prioritize behavior recommendations for management of CKD as well as assessing barriers to healthy behavior engagement. She has conducted studies that have identified high levels of substandard health behavior engagement among adults with CKD and phenotypes of behavior engagement that associate with clinical outcomes in this population. Her work also has assessed for real-time barriers to health behaviors by interviewing patients with CKD and developing a patient-centered behavioral intervention that leverages mobile health technology to increase engagement in healthy behaviors. She is currently conducting feasibility testing of the intervention in a clinical trial. Dr. Schrauben’s research aims to address implementation gaps in evidence-based CKD care. She is currently expanding her investigations in disease management by exploring the impact of functional status among those with CKD and multi-morbidity. Her future work aims to guide the development of innovative strategies to improve clinical and patient-reported outcomes in CKD.
Selected Publications
Schrauben SJ, Park D, Amaral S, Purcell A, Zhang S, Kearney M, Bilger A, Feldman HI, Dember L.: Supporting Self-Management of Healthy Behaviors in Chronic Kidney Disease: The SMART-HABITS Randomized Trial. Clinical Journal of the American Society of Nephrology. 19 (9): 1109-18,2024.
Tinaikar S, Schrauben SJ.: Social Connection: A Neglected Social Determinant of Health and an Opportunity to Improve Disease Management. American Journal of Kidney Diseases. in press : 2024.
Yeo W-J, Surapaneni AL, Hasson D, Schmidt IM, Sekula P, Kottgen A, Eckardt K-U, Rebholz CM, Yu B, Waikar SS, Rhee EP, Schrauben SJ, Fedlman HI, Vasan RS, Kimmel PL, Coresh J, Grams ME, Schlosser P.: Serum and urine metabolites and kidney function. Journal of the American Society of Nephrology 35 (9): 1252-65,2024.
Rivera E, Tintle N, Townsend RR, Rahman M, Schrauben SJ, Clark-Cutaia M, Hannan M, Lash JP, Wolfrum K, Missikpode C, Hirschman K.: Characterization of CKD Illness Representation Profiles Using Patient Level Factors. Journal of Nephrology 37 (3): 2024.
Amatruda JG, Katz R, Rehbholz CM, Sarnak MJ, Gutierrez OM, Schrauben SJ, Greenberg JH, Coresh J, Cushman M, Waikar S, Parikh CR, Schelling JR, Jogalekar MP, Bonventre JV, Vasan SR, Kimmel PL, Ix JH, Shlipak MG.: Urine Biomarkers of Kidney Tubule Health and Risk of Incident CKD in Persons without Diabetes: The ARIC, MESA and REGARDS Studies. Kidney Medicine 6 (6): 100834,2024.
Schrauben SJ, Purcell A, Bilger A, Amaral S, Feldman HI, Dember LM.: Supporting Self-Management of Healthy Behaviors (SMART-HABITS) in CKD and Hypertension: A Pilot Trial J Am Soc Nephrology 34 (suppl 1): S40,2023.
Schrauben SJ, Sapa H, Anderson AH, Hsu C-Y, Ix JH, Shafi T, Shlipak MG, Chen J, Hostetter TH, Brown J, Mehta R, Townsend RR, Seegmiller JC, Kimmel PL, Ramachandran VS, Feldman HI, Schelling JR: Association of urine and plasma ADMA with atherosclerotic cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. Nephrology, Dialysis and Transplant 38 (12): 2023.
Le D, Chen J, Shlipak MG, Ix JH, Sarnak MJ, Gutierrez OM, Schelling JR, Bonventre JV, Sabbisetti VS, Schrauben SJ, Coca SG, Kimmel PL, Ramachandran VS, Grams ME, Parikh C, Coresh J, Rebholz CM: Plasma Biomarkers and Incident CKD Among Individuals without Diabetes Kidney Medicine 5 (11): 100719,2023.
Chen J, Hamm LL, Jaar BG, He H, Zhao C, Geng S, Anderson AH, Batuman V, Bundy JD, Taliercio JJ, Rao PS, Schrauben SJ, Djokic M, Merriman J, Rodriguez Mendez deSosa GM, Go AS, Lash JP, He J.: Risk Factors for Progressive Cardiorenal Syndrome in CKD Patients J Am Soc Nephrol 34 (suppl 1): S153,2023.
Schrauben SJ, O’Brien CS, Bilger A.: Investigating Barriers to Implementation of Functional Status Assessments in CKD Care: A Mixed Methods Study Among Stakeholders J Am Soc Néphron 34 (suppl 1): S672,2023.
Academic Contact Information
Renal Division, 1 Founders
3400 Spruce St
Philadelphia,
PA
19103
Patient appointments: 800-789-7366