Description of Research Expertise

Dr. Nabavizadeh is an Associate Professor of Radiology at the Hospital of the University of Pennsylvania with a research appointment at the Children’s Hospital of Philadelphia and the imaging lead of two consortia, CBTN (The Children’s Brain Tumor Network) and PNOC (The Pacific Pediatric Neuro-oncology Consortium) respectively dedicated to biospecimen-driven data generation and precision medicine clinical trials. Dr. Nabavizadeh’s research focuses on multimodality imaging using structural and physiologic MRI imaging with additional PET probes and molecular imaging techniques to better understand the complex nature of brain tumor microenvironment. Dr. Nabavizadeh is the associate editor for the brain tumor section at the American Journal of Neuroradiology and has more than 140 peer-reviewed publications in prestigious journals such as Nature Medicine, Nature Communications, JAMA Neurology, Clinical Cancer Research, Neuro-Oncology, Radiology, and Journal of Nuclear Medicine. He has served as the principal investigator of multiple prospective imaging trials including investigator-initiated trials and industry-sponsored FDA registry trials.

Selected Publications

Mahootiha M, Tak D, Ye Z, Zapaishchykova A, Likitlersuang J, Climent Pardo JC, Boyd A, Vajapeyam S, Chopra R, Prabhu SP, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Mueller S, Aerts HJWL, Bandopadhayay P, Ligon KL, Haas-Kogan D, Poussaint TY, Qadir HA, Balasingham I, Kann BH.: Multimodal Deep Learning Improves Recurrence Risk Prediction in Pediatric Low-Grade Gliomas Neuro Oncol : 2024.

Boyd A, Ye Z, Prabhu S, Tjong MC, Zha Y, Zapaischykova A, Vajapeyam S, Catalano PJ, Hayat H, Chopra R, Liu KX, Nabavizadeh A, Resnick A, Mueller S, Haas-Kogan D, Aerts HJWL, Poussaint T, Kann BH.: Stepwise Transfer Learning for Expert-Level Pediatric Brain Tumor MRI Segmentation in a Limited Data Scenario Radiol Artif Intell . : 2024.

Maoz SL, Golzar A, Choby G, Hwang PH, Wang EW, Kuan EC, Adappa ND, Geltzeiler M, Getz AE, Humphreys IM, Le CH, Pinheiro-Neto CD, Fischer JL, Chan EP, Abuzeid WM, Chang EH, Jafari A, Kingdom TT, Kohanski MA, Lee JK, Lazor JW, Nabavizadeh A, Nayak JV, Palmer JN, Patel ZM, Resnick AC, Smith TL, Snyderman CH, St John MA, Storm PB, Suh JD, Wang MB, Sim MS, Beswick DM.: University of Washington Quality of Life subdomain outcomes after treatment of sinonasal malignancy: A prospective, multicenter study Int Forum Allergy Rhinol. : 2024.

Tak D, Garomsa BA, Zapaishchykova A, Ye Z, Vajapeyam S, Mahootiha M, Climent Pardo JC, Smith C, Familiar AM, Chaunzwa T, Liu KX, Prabhu S, Bandopadhayay P, Nabavizadeh A, Mueller S, Aerts HJ, Haas-Kogan D, Poussaint TY, Kann BH.: Longitudinal risk prediction for pediatric glioma with temporal deep learning. medRxiv : 2024.

Tak D, Ye Z, Zapaishchykova A, Zha Y, Boyd A, Vajapeyam S, Chopra R, Hayat H, Prabhu S, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Resnick A, Mueller S, Aerts HJWL, Bandopadhayay P, Ligon K, Haas-Kogan D, Poussaint T, Kann BH.: Noninvasive molecular subtyping of pediatric low-grade glioma with self-supervised transfer learning Radiol Artif Intell. 6 (3): e230333,2024.

Vossough A, Khalili N, Familiar AM, Gandhi D, Viswanathan K, Tu W, Haldar D, Bagheri S, Anderson H, Haldar S, Storm PB, Resnick A, Ware JB, Nabavizadeh A, Fathi Kazerooni A.: Training and Comparison of nnU-Net and DeepMedic Methods for Autosegmentation of Pediatric Brain Tumors. AJNR Am J Neuroradiol. : 2024.

Ramakrishnan D, Brüningk SC, von Reppert M, Memon F, Maleki N, Aneja S, Kazerooni AF, Nabavizadeh A, Lin M, Bousabarah K, Molinaro A, Nicolaides T, Prados M, Mueller S, Aboian MS.: Comparison of Volumetric and 2D Measurements and Longitudinal Trajectories in the Response Assessment of BRAF V600E-Mutant Pediatric Gliomas in the Pacific Pediatric Neuro-Oncology Consortium Clinical Trial AJNR Am J Neuroradiol. 8 (45): 475-482,2024.

Bagley SJ, Logun M, Fraietta JA, Wang X, Desai AS, Bagley LJ, Nabavizadeh A, Jarocha D, Martins R, Maloney E, Lledo L, Stein C, Marshall A, Leskowitz R, Jadlowsky JK, Christensen S, Oner BS, Plesa G, Brennan A, Gonzalez V, Chen F, Sun Y, Gladney W, Barrett D, Nasrallah MP, Hwang WT, Ming GL, Song H, Siegel DL, June CH, Hexner EO, Binder ZA, O'Rourke DM.: Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results Nat Med. : 2024.

Kim DD, Chandra RS, Yang L, Wu J, Feng X, Atalay M, Bettegowda C, Jones C, Sair H, Liao WH, Zhu C, Zou B, Kazerooni AF, Nabavizadeh A, Jiao Z, Peng J, Bai HX.: Active Learning in Brain Tumor Segmentation with Uncertainty Sampling and Annotation Redundancy Restriction J Imaging Inform Med : 2024.

Dolui S, Wang Z, Wolf RL, Nabavizadeh A, Xie L, Tosun D, Nasrallah IM, Wolk DA, Detre JA; Alzheimer's Disease Neuroimaging Initiative.: Automated Quality Evaluation Index for Arterial Spin Labeling Derived Cerebral Blood Flow Maps J Magn Reson Imaging : 2024.

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Academic Contact Information

Hospital of the University of Pennsylvania
Department of Radiology
3400 Spruce Street
Philadelphia, PA 19104