Penn Medicine Provider
Cardiology
Thomas P. Cappola, MD, ScM
4.9
(40)
Sees patients age 18 and up
Penn Heart and Vascular Center

About me

  • Chief, Division of Cardiovascular Medicine
  • William Smilow Professor

Education and training

  • Medical School: Harvard University
  • Residency: Massachusetts General Hospital/Brigham and Women’s Hospital
  • Fellowship: Johns Hopkins Hospital

What my patients think about me

Average Rating
4.9

40 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

April 2025
5.0
5.0
knows are medical issues & explains everything to our level.
April 2025
5.0
5.0
he explains an listens
February 2025
5.0
5.0
dr cappola is fantastic cardiologist excellent doctor extremely caring
December 2024
5.0
5.0
he do a thorough job and take the time to explain everything.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital
Dr. Cappola is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Azzo JD, Dib MJ, Zagkos L, Zhao L, Wang Z, Chang CP, Ebert C, Salman O, Gan S, Zamani P, Cohen JB, van Empel V, Richards AM, Javaheri A, Mann DL, Rietzschel ER, Schafer PH, Seiffert DA, Gill D, Burgess S, Ramirez-Valle F, Gordon DA, Cappola TP, Chirinos JA. Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction. , Circ Heart Fail. : 2024,e011146.


Gan S, Zhao L, Salman O, Wang Z, Ebert C, Azzo JD, Dib MJ, Zamani P, Cohen JB, Kammerhoff K, Schafer P, Seiffert DA, Ramirez-Valle F, Gordon DA, Cvijic ME, Gunawardhana K, Liu L, Chang CP, Cappola TP, Chirinos JA. Proteomic Correlates of the Urinary Protein/Creatinine Ratio in Heart Failure With Preserved Ejection Fraction. , Am J Cardiol, 206: 2023,312-319.


Guo Z, Valenzuela Ripoll C, Picataggi A, Rawnsley DR, Ozcan M, Chirinos JA, Chendamarai E, Girardi A, Riehl T, Evie H, Diab A, Kovacs A, Hyrc K, Ma X, Asnani A, Shewale SV, Scherrer-Crosbie M, Cowart LA, Parks JS, Zhao L, Gordon D, Ramirez-Valle F, Margulies KB, Cappola TP, Desai AA, Pedersen LN, Bergom C, Stitziel NO, Rettig MP, DiPersio JF, Hajny S, Christoffersen C, Diwan A, Javaheri A Apolipoprotein M attenuates athracycline cardiotoxicity and lysosomaliInjury. , JACC Basic Transl Sci, 8(3): 2023,340-355


Spurrell CH, Barozzi I, Kosicki M, Mannion BJ, Blow MJ, Fukuda-Yuzawa Y, Slaven N, Afzal SY, Akiyama JA, Afzal V, Tran S, Plajzer-Frick I, Novak CS, Kato M, Lee EA, Garvin TH, Pham QT, Kronshage AN, Lisgo S, Bristow J, Cappola TP, Morley MP, Margulies KB, Pennacchio LA, Dickel DE, Visel A Genome-wide fetalization of enhancer architecture in heart disease , Cell Rep., 40(12): 2022,111400


Chirinos JA, Zhao L, Reese-Petersen AL, Cohen JB, Genovese F, Richards AM, Doughty RN, Díez J, González A, Querejeta R, Zamani P, Nuñez J, Wang Z, Ebert C, Kammerhoff K, Maranville J, Basso M, Qian C, Rasmussen DGK, Schafer PH, Seiffert D, Karsdal M, Gordon DA, Ramirez-Valle F, Cappola TP Endotrophin, a collagen VI formation–derived peptide, in heart failure , NEJM Evidence, 1(9): 2022,EVIDoa2200091


Flam E, Jang C, Murashige D, Yang Y, Morley MP, Jung S, Kantner DS, Pepper H, Bedi KC, Brandimarto J, Prosser BL, Cappola T, Snyder NW, Rabinowitz JD, Margulies KB, Arany Z Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy , Nat Cardiovasc Res, 1: 2022,817-829


Javaheri A, Diab A, Zhao L, Qian C, Cohen JB, Zamani P, Kumar A, Wang Z, Ebert C, Maranville J, Kvikstad E, Basso M, van Empel V, Richards AM, Doughty RN, Rietzschel E, Kammerhoff K, Gogain J, Schafer P, Seiffert DA, Gordon DA, Ramirez-Valle F, Mann DL, Cappola TP, Chirinos JA Proteomic analysis of effects of spironolactone in heart failure with preserved ejection fraction , Circ Heart Fail , 15(9): 2022,e009693


Reza N, Edwards JJ, Katcoff H, Mondal A, Griffis H, Rossano JW, Lin KY, Holzhauser HL, Wald JW, Owens AT, Cappola TP, Birati EY, Edelson JB Sex differences in left ventricular assist device-related emergency department encounters in the United States. , J Card Fail, 28(9): 2022,1445-1455


Lumbers RT, Shah S...Cappola TP, Ellinor PT, Vasan RS, Smith JG The genomics of heart failure: design and rationale of the HERMES consortium , ESC Heart Fail , 8(6): 2021,5531-5541


McAfee Q, Chen CY, Yang Y, Caporizzo MA, Morley M, Babu A, Jeong S, Brandimarto J, Bedi KC Jr, Flam E, Cesare J, Cappola TP, Margulies K, Prosser B, Arany Z. Truncated titin proteins in dilated cardiomyopathy , Sci Transl Med, 13(618): 2021,eabd7287


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