Selected Publications
Meghan Logun, Xin Wang, Yusha Sun, Stephen J Bagley, Nannan Li, Arati Desai, Daniel Y Zhang, MacLean P Nasrallah, Emily Ling-Lin Pai, Bike Su Oner, Gabriela Plesa, Donald Siegel, Zev A Binder*, Guo-Li Ming*, Hongjun Song*, Donald M O'Rourke*: Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy Cell Stem Cell S1934-5909 (24): 00409-0,2024.
Daniel H Park, Pratik S Bhojnagarwala, Kevin Liaw, Devivasha Bordoloi, Nicholas J Tursi, Shushu Zhao, Zev A Binder, Donald O’Rourke, and David B Weiner: Novel tri-specific T-cell engager targeting IL-13Rα2 and EGFRvIII provides long-term survival in heterogeneous GBM challenge and promotes antitumor cytotoxicity with patient immune cells Journal for ImmunoTherapy of Cancer 12 (12): e009604,2024.
Akbari H, Bakas S, Sako C, Fathi Kazerooni A, Villanueva-Meyer J, Garcia JA, Mamourian E, Liu F, Cao Q, Shinohara RT, Baid U, Getka A, Pati S, Singh A, Calabrese E, Chang S, Rudie J, Sotiras A, LaMontagne P, Marcus DS, Milchenko M, Nazeri A, Balana C, Capellades J, Puig J, Badve C, Barnholtz-Sloan JS, Sloan AE, Vadmal V, Waite K, Ak M, Colen RR, Park YW, Ahn SS, Chang JH, Choi YS, Lee SK, Alexander GS, Ali AS, Dicker AP, Flanders AE, Liem S, Lombardo J, Shi W, Shukla G, Griffith B, Poisson LM, Rogers LR, Kotrotsou A, Booth TC, Jain R, Lee M, Mahajan A, Chakravarti A, Palmer JD, DiCostanzo D, Fathallah-Shaykh H, Cepeda S, Santonocito OS, Di Stefano AL, Wiestler B, Melhem ER, Woodworth GF, Tiwari P, Valdes P, Matsumoto Y, Otani Y, Imoto R, Aboian M, Koizumi S, Kurozumi K, Kawakatsu T, Alexander K, Satgunaseelan L, Rulseh AM, Bagley SJ, Bilello M, Binder ZA, Brem S, Desai AS, Lustig RA, Maloney E, Prior T, Amankulor N, Nasrallah MLP, O'Rourke DM, Mohan S, Davatzikos C; ReSPOND consortium: Machine Learning-based Prognostic Subgrouping of Glioblastoma: A Multi-center Study Neuro-Oncology : 2024.
Nannan Li, Jesse L. Rodriguez, Yibo Yin, Meghan T Logun, Logan Zhang, Shengkun Yu, Kelly A. Hicks, Vicky Zhang, Laura Zhang, Chuncheng Xie, Jiabin Wang, Joseph A Fraietta, Zev A. Binder*, Zhiguo Lin*, and Donald M. O’Rourke*: Armored Bicistronic CAR T Cells with Dominant-negative TGF-β Receptor II to Overcome Resistance in Glioblastoma Mol Ther 32 (10): 3522-3538,2024.
Elinor Willis, Jillian Verrelle, Esha Banerjee, Charles-Antoine Assenmacher, James C. Tarrant, Nicholas Skuli, Moriah L. Jacobson, Donald M. O’Rouke, Zev A. Binder*, and Enrico Radaelli1*: Humanization with CD34-positive hematopoietic stem cells in NOG-EXL mice results in improved long-term survival and less severe myeloid cell hyperactivation phenotype relative to NSG-SGM3 mice Veterinary Pathology 61 (4): 664-674,2024.
Jingxian Liu, Song Cao, Kathleen J. Imbach, Marina A. Gritsenko, Tung-Shing M. Lih, Jennifer E. Kyle*, Tomer M. Yaron*, Zev A. Binder*, Yize Li*, Ilya Strunilin*, Yi-Ting Wang*, Chia-Feng Tsai*, Weiping Ma*, Lijun Chen*, Natalie M. Clark, Andrew Shinkle, Nataly Naser Al Deen, Wagma Caravan, Andrew Houston, Faria A. Simin, Matthew A. Wyczalkowski, Liang-Bo Wang, Erik, Storrs, Siqi Chen, Ritvik Illindala, Yuping D. Li, Reyka G. Jayasinghe, Dmitry Rykunov, Sandra L. Cottingham, Rosalie K. Chu, Karl K. Weitz, Ronald J. Moore, Tyler Sagendorf, Vladislav A. Petyuk, Michael Nestor, Lisa M. Bramer, Kelly G. Stratton, Athena A. Schepmoes, Sneha P. Couvillion, Josie Eder, Young-Mo Kim, Yuqian Gao, Thomas L. Fillmore, Rui Zhao, Matthew E. Monroe, Austin N. Southard-Smith, Yang E. Li, Rita Jui-Hsien Lu, Jared L. Johnson, Maciej Wiznerowicz, Galen Hostetter, Chelsea J. Newton, Karen A. Ketchum, Ratna R. Thangudu, Jill S. Barnholtz-Sloan, Pei Wang, David Fenyö, Eunkyung An, Mathangi Thiagarajan, Ana I. Robles, D. R. Mani, Richard D. Smith, Eduard Porta-Pardo, Lewis C. Cantley, Antonio Iavarone, Feng, Chen, Mehdi Mesri, MacLean P. Nasrallah, Hui Zhang, Adam C. Resnick, Milan G. Chheda, Karin D. Rodland, Tao Liu, Li Ding, Philadelphia Coalition for a Cure, Clinical Proteomic Tumor Analysis Consortium: Multi-scale signaling and tumor evolution in high-grade gliomas Cancer Cell 42 (7): 1217-1238.e19,2024.
Stephen J. Bagley, Meghan Logun, Joseph A. Fraietta, Xin Wang, Arati S. Desai, Linda J. Bagley, Danuta Jarocha, Rene Martins, Eileen Maloney, Lester Lledo, Carly Stein, Amy Marshall, Rachel Leskowitz, Julie K. Jadlowsky, Shannon Christensen, Bike Su Oner, Gabriela Plesa, Andrea Brennan, Vanessa Gonzalez, Fang Chen, Yusha Sun, Whitney Gladney, David Barrett, Ali Nabavizadeh, MacLean P. Nasrallah, Wei-Ting Hwang, Guo-Li Ming, Hongjun Song, Donald L. Siegel, Carl H. June, Elizabeth O. Hexner, Zev A. Binder*, Donald M. O'Rourke*: Intrathecal Bivalent CAR T Cells Targeting EGFR and IL13Rα2 in Recurrent Glioblastoma: Phase 1 Trial Interim Results Nat Med 30 (5): 1320-1329,2024.
David E. Reynolds, Yusha Sun, Xin Wang, Phoebe Vallapureddy, Jianhua Lim, Menghan Pan, Andres Fernandez Del Castillo, Jonathan C. T. Carlson, Mark A. Sellmyer, Maclean Nasrallah, Zev Binder, Donald M. O’Rourke, Guo-li Ming, Hongjun Song, and Jina Ko: Live Organoid Cyclic Imaging Adv Sci (Weinh) 11 (14): e2309289,2024.
Stephen J. Bagley*, Zev A. Binder*, Lamia Lamrani*, Eliana Marinari, Arati S. Desai, MacLean P. Nasrallah, Eileen Maloney, Steven Brem, Robert A. Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Pierre-Emmanuel Bonté, Christel Goudot, Wilfrid Richer, Eliane Piaggio, Shawn Kothari, Lea Guyonnet, Coralie L. Guerin, Joshua J. Waterfall, Suyash Mohan, Wei-Ting Hwang, Oliver Y. Tang, Meghan Logun, Meghna Bhattacharyya, Kelly Markowitz, Devora Delman, Amy Marshall, E. John Wherry, Sebastian Amigorena, Gregory L. Beatty, Jennifer L. Brogdon, Elizabeth Hexner, Denis Migliorini, Cecile Alanio & Donald M. O’Rourke: Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial Nature Cancer 5 (3): 517-531,2024.
Jun Guo, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Fanyang Yu, Chiharu Sako, Elizabeth Mamourian, Russell T. Shinohara, Constantinos Koumenis, Stephen J. Bagley, Jennifer J. D. Morrissette, Zev A. Binder, Steven Brem, Suyash Mohan, Robert A. Lustig, Donald M. O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean P. Nasrallah & Christos Davatzikos: Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach Sci Rep 14 (1): 4922,2024.
View all publications
Academic Contact Information
3600 Hamilton Walk
Stemmler Hall
Philadelphia,
PA
19104
Phone: 215-573-0837