Trust Penn Medicine for top-tier prostate cancer treatment and care

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As a top leader in the region, you'll find unmatched prostate cancer treatment and support that goes the extra mile. Our team of genitourinary (GU) and urologic oncology experts at the Abramson Cancer Center tailor each patient’s care plan to their unique needs, resulting in quicker recovery times and a comfortable experience.

Choose Penn for Advanced Prostate Cancer Care

Whether you are newly diagnosed or seeking a second opinion, our comprehensive prostate cancer program provides access to the latest treatments and additional unique benefits that consistently result in better outcomes.

A team of specialists: Our nationally recognized prostate cancer team includes experts in surgery, prostate cancer genetics, radiation and medical oncology who have all completed the highest level of training in prostate cancer. These specialists work side by side to determine a personalized care plan, putting you on the path to a faster recovery.

Proton therapy: When you choose Penn Medicine, you’re choosing advanced treatments, such as proton therapy. We're home to one of the largest proton therapy centers not just in the region but in the world. Proton therapy is the most advanced form of radiation ever developed, and our specialists possess a breadth of knowledge about this targeted method, which aids in reducing side effects.

Active surveillance plans: For slow-growing prostate cancers, doctors may recommend a personalized surveillance plan in order to discover early signs that the cancer is worsening. This may help you avoid more invasive treatments like surgery and radiation, and their side effects.

Advanced technology: Our state-of-the-art MRI-ultrasound technology provides us with detailed and real-time ultrasound imaging, allowing for a more precise view of the prostate. Meanwhile, liquid biopsies analyze cancer DNA, helping us identify the most effective treatments to block cancer growth. Our team also uses an MR simulator, which works to enhance the safety and efficacy of your radiation treatment based on the position of your body. Lastly, our cancer center partners with our fertility preservation program to offer patients support regarding family planning.

Understanding Our Treatment Options and Innovative Approach

Addressing your diagnosis is the first step; from there we’ll take your overall health, genetic profile, lifestyle, and core values into account when creating your personalized treatment plan. Your doctor may choose one or more of the following treatments:

  • Active surveillance: non-invasive management of your cancer that includes exams and advanced biopsies
  • Surgery: this is a common path forward for many patients. With usage of techniques such as robotic prostatectomy, our surgical team is nationally recognized as one of the best.
  • Radiation: a less invasive option that uses X-rays to kill cancer cells.
  • Brachytherapy: we offer high dose rate brachytherapy—a catheter-based method—that directly treats the tumor.
  • High-intensity focused ultrasound: a cutting-edge procedure that directly destroys cancer cells.
  • Therapy: there are various types of therapy; including proton, hormone, targeted, immuno, chemo, and salvage. Our expert oncologists will guide you towards the right course of action.

Throughout your treatment and care journey, our multidisciplinary team of experts is dedicated to prioritizing your safety, comfort, and quality of life, so you can get back to you. Our world-class urologists will also address sexual function with you after treatment, providing options that grant you a little more peace of mind.

Locations Near You

Whether you’re coming from Philadelphia, New Jersey, or the surrounding suburbs, you’ll be supported by an exceptional and compassionate team of specialists. Depending on your diagnosis and care plan, our team will connect you with the right specialists for your care.


Perelman Center for Advanced Medicine

3400 Civic Center Blvd, Philadelphia, PA 19104

Pennsylvania Hospital

800 Spruce St, Philadelphia, PA 19107

Penn Presbyterian Medical Center

51 N 39th St, Philadelphia, PA 19104

Penn Medicine University City

3737 Market St, Philadelphia, PA 19104

Penn Medicine Cherry Hill

1865 NJ-70, Cherry Hill Township, NJ 08003

Penn Medicine Radnor

145 King of Prussia Rd, Radnor, PA 19087

Penn Medicine Valley Forge

1001 Chesterbrook Blvd, Berwyn, PA 19312