May Penn Trauma Reports Feature Beta-Blockade in Traumatic Brain Injury, The Lasting Effects of Traumatic Injury, Firearm Epidemiology in Philadelphia, More

Each month, the Penn Physician Blog features a review of recent journal publications by clinical researchers / clinicians in the Department of Traumatology, Surgical Critical Care and Emergency Surgery at the University of Pennsylvania.

In May 2022, the publications from Penn Trauma reflected both the clinical concentrations and the practical realities of one of the region's busiest urban Trauma Departments. In addition to studies of beta blocker blockade in traumatic brain injury and pre-intervention computed tomography in patients with abdominopelvic trauma, Penn Trauma articles provided an overview of equity, disparities in insurance coverage, the changing epidemiology of firearm violence in Philadelphia, and other issues of concern to the Trauma community.

Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo.

Lopez AJ, ElSaadani M, Jacovides CL, George A, Culkin MC, Ahmed S, Kumar MA, Kaplan LJ, Smith DH, Pascual JL.

To evaluate the mechanisms of beta-blockade in improved survival in traumatic brain injury (TBI), Penn Trauma researchers investigated the dose-dependent effects of beta blockade on penumbral blood brain barrier leukocyte mobilization and permeability post-TBI.

Beyond Pain and Disability: the Lasting Effects of Trauma on Life after Injury

Hatchimonji JS, Kaufman EJ, Babalola D, Candido K, Chreiman K, Jackson S, Reilly PM, Seamon MJ.

A Penn Trauma investigation of patients at the Penn Level I trauma center at admission and 6 months afterward finds that the effects of injury extend beyond pain and disability to impact several realms of life for at least 6 months following trauma.

The changing epidemiology of interpersonal firearm violence during the COVID-19 pandemic in Philadelphia, PA.

Afif IN, Gobaud AN, Morrison CN, Jacoby SF, Maher Z, Dauer ED, Kaufman EJ, Santora TA, Anderson JH, Pathak A, Sjoholm LO, Goldberg AJ, Beard JH.

A descriptive six-year epidemiologic study from Penn Trauma and Family and Community Health, et al, using the Philadelphia Police Department registry of individuals shot and/or killed due to interpersonal firearm violence in the city. Includes a comparison of victim and event characteristics before and after the implementation of pandemic containment measures.

New Research from Penn Trauma

The following represents a selection from various publications of new studies and reports from providers in the Department of Traumatology, Surgical Critical Care and Emergency Surgery at the Perelman School of Medicine:

• Comparison of two screeners predicting the future development of depression and posttraumatic stress disorder in Black men after serious injury.
  • May 2022. Injury.
• Disparities in Insurance Status Are Associated With Outcomes but Not Timing of Trauma Care.
  • May 2022. Journal of Surgical Research.
• Professionalism of Admitting and Consulting Services and Trauma Patient Outcomes.
  • May 2022. Annals of Surgery.
• Admission Triage With Pain, Inspiratory Effort, Cough Score can Predict Critical Care Utilization and Length of Stay in Isolated Chest Wall Injury.
  • May 2022. Journal of Surgical Research.
• Improving Post-Injury Care: Key Family Caregiver Perspectives of Critical Illness After Injury.
  • May 2022. Critical Care Explorations.
• Compounding Trauma: the Intersections of Racism, Law Enforcement, and Injury.
  • May 2022. Current Trauma Reports.
• Pre-Intervention Computed Tomography Improves Performance of Endovascular Intervention in Patients with Abdominopelvic Trauma.
  • May 2022. Journal of Vascular and Interventional Radiology.
• Remaining mission-focused amid both turbulence and transition.
  • May 2022. Journal of Trauma and Acute Care Surgery.