Dr. Ed Morrisey's lab also has a strong focus on the development and regeneration of the cardiovascular system. His ultimate goal is to better understand how signaling and epigenetic pathways, regulate development and regeneration of the lungs and heart, leading to the development of new therapeutic approaches for lung and cardiac diseases.
Specific Projects include:
- How Wnt signaling, non-coding RNAs, forkhead transcription factors, and epigenetic mechanisms regulate pulmonary and cardiovascular development
- Defining how the pulmonary and cardiovascular systems co-develop i.e. How do the pulmonary vessels form?
- Determine how developmental pathways reactivated in the adult lung and whether they are critical to the repair and regeneration after injury or in disease states.