Deborah J. Culley, MD, has a longstanding interest in perioperative neurocognitive disorders (PND). This interest includes studies on the effects of anesthesia and surgery on the aged brain with a particular emphasis on postoperative delirium and persistent postoperative cognitive dysfunction and the development of screening tools that can identifying patients at greatest risk allowing precious health care resources to be aimed at patients at greatest risk.
Maryellen F Eckenhoff, PhD, is interested in the behavioral and pathologic consequences of exposure to anesthesia and surgery, especially in the context of a brain made vulnerable by the extremes of age, or other neuropathology.
Roderic G Eckenhoff, MD, is interested in the molecular underpinnings of anesthetic neurotoxicity, and serves as the chief scientific officer of the American Society of Anesthesiologists Brain Health Initiative.
Huafeng Wei, MD, PhD, focuses on calcium dysregulation as a mechanism of both anesthetic neurotoxicity as well as the neurodegeneration that underlies Alzheimer's disease.