Our research faculty lead diverse programs funded by the National Institutes of Health, foundations, and corporate sponsors with in the rich of environment of the Perelman School of Medicine. These programs leverage Penn's many institutes and centers, including the Penn Cardiovascular Institute, the Institute for Translational Medicine and Therapeutics, the Institute for Diabetes, Obesity and Metabolism, the Leonard Davis Institute for Health Economics, and the Center for Clinical Epidemiology and Biostatistics. Please see below for more detail.
Arany Lab
The Arany lab pursues a mechanistic understanding of metabolism in the cardiovascular system, and its impact on diabetes, heart failure, and other metabolic diseases. The lab incorporates a wide range of approaches, from basic molecular biology to human genetics and whole-organism metabolism.
Learn more about the Arany Lab
Cappola Lab
The Cappola Lab focuses on heart failure mechanisms, genomics, and therapeutics with an emphasis on studies in human subjects
Day Lab
The Day Lab focuses on genetic heart muscle diseases. The research program integrates translational and clinical science, with a primary focus on hypertrophic cardiomyopathy. Understanding the full spectrum of disease evolution and progression, from the primary effects of sarcomere gene mutations in cardiac muscle cells to the phenotypic expression and predictors of adverse outcomes in patients.
Epstein Lab
The Epstein Lab focuses on stem cell and developmental biology with an emphasis on epigenetics and nuclear architecture.
Kahn Lab
The Kahn Lab investigates many aspects of vascular and cardiovascular biology, including blood and lymphatic vascular development and disease, and the role of fluid forces in cardiovascular biology, and hemostasis.
Learn more about the Kahn Lab
Kelly Lab
The Kelly Lab is interested in the control of energy metabolism and mitochondrial function in the developing and diseased heart.
Learn more about the Kelly Lab
Ky Lab
The Ky Lab is interested in understanding the biologic and functional cardiovascular effects of cancer therapies in humans.
Learn more about the Ky Lab
Kimmel Lab
Dr. Kimmel performs research aimed at improving the use of existing cardiovascular therapies through personalized medicine, behavioral interventions, and novel adherence methods.
- Steven Kimmel, MD
Professor of Medicine and Epidemiology; Director, Division of Clinical Epidemiology
Director, Center for Therapeutic Effectiveness Research (CTER)
stevek@pennmedicine.upenn.edu
Learn more about the Center for Therapeutic Effectiveness Research (CTER)
Margulies Lab
The Margulies Lab examines mechanisms of myocardial structural and functional remodeling to identify targets for therapeutic interventions.
Learn more about the Margulies Lab
Morrisey Lab
The goal of the Morrisey Lab is to define the molecular mechanisms underlying lung and cardiac development and tissue regeneration using a multi-platform approach including animal and human model systems.
- Edward Morrisey, PhD
Professor of Cell and Developmental Biology
Director, Penn Center for Pulmonary Biology
The Robinette Foundation Professor of Cardiovascular Medicine
Scientific Director, Penn Institute for Regenerative Medicine
emorrise@pennmedicine.upenn.edu
Learn more about the Morrisey Lab
Musunuru Lab
The Musunuru Lab focuses on the genetics of cardiovascular and metabolic diseases and seeks to identify naturally occurring genetic variants that predispose to or protect against disease and can be used to develop therapies to protect the entire population.
Scherrer-Crosbie Lab
The Scherrer-Crosbie Lab is interested in better understanding and detecting subclinical myocardial disease in cancer and in metabolic and adipose dysfunction.