For over forty years, Joan DuPont was a cornerstone of the Scheie Eye Institute’s clinical research enterprise, her career mirroring the evolution of ophthalmology—from its analog roots to its digital; cutting-edge present. Joan’s journey, marked by significant contributions to clinical trials and patient care, offers a detailed map of the advancements in eye research and the tangible benefits these have brought to patients worldwide. DuPont's career began in an era dominated by paper charts and manual processes. She vividly recalls the meticulous work required in those early days, particularly her contributions to blood flow measurements with laser Doppler flowmetry at the Vivian Lascaux Reese Research Laboratory. This work was groundbreaking, laying the foundation for a better understanding of ocular diseases like glaucoma and diabetic retinopathy.
Outward—beyond her extensive clinical trial contributions—DuPont's legacy is marked by her ability to forge lasting relationships within the medical community and with patients. Initiatives like forming a team for the Foundation Fighting Blindness VisionWalk not only raised significant funds for research but also fostered a strong sense of community and camaraderie within Scheie. This effort, which grew from 30 to over 100 participants under her leadership, became a cherished department tradition, enhancing both team spirit and public awareness about eye diseases.
One of the most impactful aspects of DuPont’s work has been the deep, lasting connections she formed with patients, particularly those involved in long-term clinical trials. Over 40 years, she got to know patients and their families, following their journeys, celebrating their successes, and offering support during challenges. The profound impact she made on their lives is evidenced by the numerous heartfelt letters of gratitude she received, underscoring the human connection at the core of her work.
Throughout her career, DuPont has been both a mentor and a mentee. She highlights the influence of Alexander (Sandy) Brucker, MD, who she describes as a pivotal figure in her professional development. Under his guidance, she honed her skills in clinical research, contributing to pivotal trials that have shaped current treatment paradigms. Her role in transitioning from basic to clinical research was not just a career shift but a realization of her calling, driven by the tangible impact she could have on patients' lives. In years to come, DuPont is optimistic about the role of artificial intelligence in revolutionizing eye care, foreseeing a future where technology enables earlier detection and intervention for eye diseases. Her insights into the potential of AI to transform patient care are part of the broader vision that has characterized the evolution of the field.
One of the most compelling aspects of DuPont's career is the continuity of care and research. From participating in groundbreaking studies like the DCCT, which transformed diabetes management, to witnessing the advent of treatments that preserved vision for AMD patients, her work has contributed to significant milestones in ophthalmology.
In retirement, DuPont reflects on a career that was as much about building relationships as it was about contributing to the science of ophthalmology. DuPont’s journey represents the profound impact dedicated individuals can have in the medical field through consistent, committed work that advances our understanding and treatment of disease.
by Maressa Park