Research Projects for Medical Students, Residents, and Fellows

Updated 10/31/24

Students, Residents, and Fellows: Please send emails with your CV, desired start and end dates, and mention any relevant prior experience in the email. Faculty are generally more likely to be willing to mentor a student who can work for longer stretches of continuous time such as during a 5 month scholarly pursuit or a year out between 3rd and 4th year.

Vivian Lee

Corneal epithelium and nerve cross talk during regeneration

Type: Basic

Project Description: Students will be involved on a project to understand how the corneal epithelium supports corneal nerve regeneration and vice versa with an emphasis on Schwann cells as being a hub for cross-communication. As such, students will have the opportunity to assist with surgical mouse models of corneal nerve degeneration and dry eyes disease; in vivo mouse imaging; and histomorphologic evaluation of corneas.

Time Commitment: Quite flexible

Gui-Shuang Ying

Ophthalmic Research through Analysis of Publicly Available Data (All-of-Us, DRCRnet, etc.)

Type: Patient-oriented Research

Project Description: The student will develop skills in performing literature reviews, developing research proposals, gaining knowledge in statistical analysis of eye data and interpretation of analysis results (statistical analysis will be performed by a biostatistician), leading (first-authored) the development of the manuscript, and having the opportunity to present research findings at the professional conference.

Time Commitment: Flexible

Jessica Morgan

Photoreceptor imaging in health and disease using adaptive optics ophthalmoscopy

Type: Patient oriented / translational

Project Description: Students will learn about photoreceptor structure and function in retinal disease compared to normal.

Time Commitment: Preference will go to students willing to commit to longer time periods. Preference is to accept year out students over part time students.

Qi Cui

Glp1 receptor agonists for glaucoma neuroprotection

Project Description: Glaucoma pathogenesis and associated risk factors

Project Type: Basic, clinical, and translational

Project Description: Please refer to the website for current and ongoing projects.

Time Commitment: Flexible

Joan O'Brien

Glaucoma Genetics

Project Description: The project would be investigating the role of the three variants thought to be causal for glaucoma in our Cell publication.

Time Commitment: Year off students only, as currently full with shorter term students

Peter Quinn

Disease Modeling and Therapy Development for Ophthalmic Genetic Diseases

Type: Translational

Project Description: The student will learn to implement Prime Editing for the installation and correction of mutations in genes leading to ophthalmic genetic disease. This will involve editing design, molecular biology, cell culture -iPSCs, retinal organoid differentiation, large therapeutic screens, and the use of PCR, rtPCR, ddPCR, western blot and next generation sequencing workflows.

Time Commitment: Full-time only

Katherine Uyhazi

Developing gene and cell therapies for inherited retinal disease

Type: Basic science

Note: No current lab space, but interested in hosting med students in future years.

Project Description: Participate in cutting edge research to understand photoreceptor development and investigate novel treatments for blindness

Time Commitment: Summer or year-long position

Rithu Ramachandran

Utilizing large data sources to understand how social determinants of health impact eye health outcomes

Dwight Stambolian

Differentiation of stem cells to Retinal Pigment Epithelial (RPE) Cells

Type: Basic/Translational

Project Description: Learn how to perform tissue culture, work with stem cells and assess quality of differentiation to RPE cells.

Joshua Dunaief

Generating mouse models of age-related macular degeneration and testing therapeutics

Type: Basic/translational

Project Description: Learn in vivo retinal imaging in mice, eye dissection, immunohistochemistry, qPCR, Western blotting, single-cell transcriptomics

Availability: Next available position: June 2025

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