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Valerie L. Luks, MD, MHS

Valerie Luks
Medical School: Yale University School of Medicine Undergraduate: Tufts University

About Dr. Luks

Valerie Luks is a chief resident in General Surgery. She graduated with her Bachelor of Science in Biomedical Engineering from Tufts University in 2011. She then spent two years working in a Genetics Lab at the Boston Children’s Hospital before attending Yale University School of Medicine. At Yale she completed an additional year of research in which she obtained her Masters in Health Sciences before completing her medical degree in 2018. She plans to pursue a career in academic medicine.

Education

2016 - 2018
Yale University School of Medicine
Masters in Health Sciences     

Societies

  • American College of Surgeons
  • Association for Academic Surgery

Awards

2018
Ferris Prize for Outstanding Thesis
Yale University School of Medicine

2017
Samuel Jordan Graham Scholarship in Academic Surgery
Yale University Department of Surgery

2016
Translational Research Fellowship
National Institutes of Health

2012
Norman Brown Award
Pediatric Pathology Society

Research

June 2014 - May 2018
Yale School of Medicine, Department of Pediatric Surgery
Mentor: Dr. David Stitelman

June 2016 - June 2018
Yale School of Medicine, Department of Trauma Surgery
Mentor: Dr. Kevin Pei

June 2011 - August 2013
Boston Children’s Hospital, Harvard Genetics
Mentors: Dr. Kyle Kurek and Dr. Matthew Warman

June 2010 - May 2011
Tufts University, Department of Biomedical Engineering
Mentor: Dr. David Kaplan

Publications

Peer-Reviewed Manuscripts

  1. Barclay SF, Inman KW, Luks VL, McIntrye JB, Al-Ibraheemi A, Church AJ, Perez-Atayde AR, Mangray S, Jeng M, Kreimer SR, Walker L, Fishman SJ, Alomari AI, Chaudry G, Trenor III CC, Adams D, Kozakewich HPW, Kurek KC. A somatic activating NRAS variant associated with kaposiform lymphangiomatosis. Genet Med. 21(7). 2019.
  2. Luks VL, Merola J, Arnold BN, Ibarra C, Pei KY. Prophylactic Ureteral Stenting in Laparoscopic Colectomy; Revisiting Traditional Practice. J Surg Res. 234. 2019.
  3. Ricciardi A, Bahal R, Farrelly J, Quijano E, Bianchi A, Luks VL, Putnam R, Lopez F, Coskun S, Song E, Liu Y, H W-C, Ly D, Stitelman DH, Glazer P, Saltzman WM. In utero nanoparticle delivery for site-specific genome editing. Nat Comm. 9(2481). 2018.
  4. Merola J, Arnold B, Luks VL, Ibarra C, Resio B, Davis KA, Pei KY. Prophylactic Ureteral Stent Placement vs No Ureteral Stent Placement During Open Colectomy. JAMA Surg. 153(1): 87-90. 2017.
  5. Luks VL, Kamitaki N, Vivero MP, Uller W, Rab R, Bovee JV, Rialon KL, Guevara CJ, Alomari AI, Greene AK, Fishman SJ, Kozakewich HP, Maclellan RA, Mulliken JB, Rahbar R, Spencer SA, Trenor CC III, Upton J, Zurakowski D, Perkins JA, Kirsh AL, Bennett JT, Dobyns WB, Kurek KC, Warman M, McCarroll SA, Murillo R. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 166(4): 1048-1054. 2015.
  6. Boscolo E, Coma S, Luks VL, Greene AK, Klagsbrun M, Warman ML, Bischoff J. AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation. Angiogenesis. 18 (2): 151-162, 2015.
  7. Luks V, Moores C, Villalona G, Stitelman DH, Caty MG. Successful non-operative management of a contained tracheal tear following iatrogenic endotracheal tube injury. J Pediatr Surg Case Rep. 2:524-526, 2014.
  8. Maclellan RA, Luks VL, Vivero MP, Mulliken JB, Zurakowski D, Padwa BL, Warman ML, Greene AK, Kurek KC. PIK3CA activating mutations in facial infiltrating lipomatosis. Plast Reconstr Surg. 133: 12e-9e, 2014.
  9. Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Bowen ME, Yamamoto GL, Kozakewich HPW, Warman ML. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet. 90: 1108-1115, 2012.

Oral Abstracts

  1. Luks VL. Effect of Trauma Center Designation on Mortality After Adolescent Firearm Injury. Templeton Pediatric Trauma Symposium, March 2020, Philadelphia, PA.
  2. Luks VL. Targeted Nanoparticle Delivery for In Utero Treatment of Congenital Disorders. Plenary Scientific Session for Award Winning Theses at Yale School of Medicine Student Research Day, May 2018, New Haven, CT.
  3. Luks VL, Merola J, Dong H, Li F, Pei KY. Failure of Non-Operative Management for Acute Diverticulitis. Academic Surgical Congress, January 2018, Jacksonville, FL.
  4. Luks VL, Merola J, Pei KY. Prophylactic Ureteral Stenting in Patients Undergoing Laparoscopic Colectomy: Revisiting Traditional Practice. New England Surgical Society Surgical Resident and Fellow Research Presentation Day, May 2017, Waltham, MA.
  5. Luks VL, Ricciardi AS, Farrelly JS, Saltzman WM, Egan ME, Stitelman DH. In Utero Gene Therapy: Targeted Nanoparticles for Correction of Cystic Fibrosis. Cystic Fibrosis Interest Group Invited Speaker, April 2017, New Haven, CT.
  6. Luks VL, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Kozakewich HPW, Warman ML, Kurek KC. CLOVES and Klippel-Trenaunay Syndromes Share Somatic Mosaic Activating Mutations in PIK3CA. Pediatric Pathology Society Annual Meeting, October 2012, Madrid, Spain.

Poster Presentations

  1. Luks VL, Tietjen GT, Farrelly JS, Saltzman WM, Egan ME, Stitelman, DH. Cell-specific targeting increases intracellular uptake of nanoparticles in cystic fibrosis bronchial epithelial cells. The American Society of Gene & Cell Therapy Annual Meeting, May 2017, Washington DC.
  2. Farrelly JS, Bianchi AH, Ricciardi AS, Ahle SL, Luks VL, Saltzman WM, Stitelman DH. Intra-Amniotic Delivery of Biodegradable Microparticles and Nanoparticles to the Spinal Defect in Rat Myelomeningocele Model. The American Society of Gene & Cell Therapy Annual Meeting, May 2017, Washington DC.
  3. Luks VL, Ricciardi AS, Tietjen GT, Saltzman WM, Egan ME, Stitelman DH. Cell-specific targeting enhances nanoparticle uptake for in utero genetic correction of cystic fibrosis. 2017 Yale Pediatric Research Forum, May 2017, New Haven, CT.
  4. Luks VL, Merola J, Arnold B, Ibarra C, Pei KY. Prophylactic Ureteral Stenting in Patients Undergoing Laparoscopic Colectomy: Revisiting Traditional Practice. New England Surgical Society Annual Meeting, September 2017, Bretton Woods, NH.
  5. Ahle SL, Farrelly JS, Ricciardi AS, Luks VL, Saltzman WM, Stitelman DH. Characterizing the Biodistribution of Intravenously and Intra-amniotically Injected Nanoparticles in Rat Fetuses. New England Surgical Society Annual Meeting, September 2017, Bretton Woods, NH.
  6. Luks VL, Tietjen GT, Farrelly JS, Ahle S, Saltzman WM, Egan ME, Stitelman DH. Cell-specific Targeting Increases Intracellular Uptake of Nanoparticles in Cystic Fibrosis Bronchial Epithelial Cells. North American Cystic Fibrosis Conference, November 2017, Indianapolis, IN.
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