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Jack S. DePaolo, MD, PhD

Jack Depaolo
Medical School: Louisiana State University Health Sciences Center New Orleans

About Dr. DePaolo

Jack is a CY4 categorical surgery resident after completing an intern year in Pediatrics at CHOP and a prelim General Surgery year at Penn. He is undifferentiated at this point but has interests in cardiac surgery, trauma/critical care, and pediatric surgery. He is interested in basic research and plans on being a surgeon-scientist in whatever field he selects.

Societies

  • American Association for Cancer Research
  • American Medical Student Association
  • American Physician Scientist Association
  • American Heart Association

Research

2017 - 2018
Comparison of Short Term Outcomes In Patients With Single Ventricle Heart Disease Eligible for Inclusion of Antegrade Pulmonary Blood Flow as Part of the Bidirectional Glenn Circuit

2011 - 2015
The role of ARD1 in AR activation and prostate tumorigenesis

Publications

  1. Bauser-Heaton H, Qureshi AM, Goldstein BH, Glatz AC, Nicholson GT, Meadows JJ, Depaolo J, McCracken C, Mossad E, Wilson E, Petit CJ. Percutaneous Patent Ductus Arteriosus Stenting Using the Carotid or Axillary Artery: A Multicenter Study from the Congenital Catheterization Research Collaborative. In preparation for submission for publication to Pediatric Cardiology.
  2. DePaolo, J.,* Wang, Z.,* Guo, J., Zhang, G., Qian, C., Zhang, H., Zabaleta, J., & Liu, W. Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis. Oncotarget, 7(44), 71417-71428.
  3. Liu, Z., Rebowe, R. E., Wang, Z., Li, Y., Wang, Z., DePaolo, J., Guo, J., Qian, C., Liu, W. KIF3a Promotes Proliferation and Invasion via Wnt Signaling in Advanced Prostate Cancer. Molecular Cancer Research : MCR, 12(4), 491–503. doi: 10.1158/1541-7786.
  4. DePaolo, J., and Barbeau, J., Enhanced Tissue Tracking: Addressing a Grave Problem. JAMA. 2013 Feb 6;309(5):443-4.
  5. Velayati, A.*, DePaolo, J.*, Gupta, N., Choi, J. H., Moaven, N., Westbroek, W., Goker-Alpan, O., Goldin, E., Stubblefield, B. K., Kolodny, E., Tayebi, N. and Sidransky, E. (2011), A mutation in SCARB2 is a modifier in Gaucher disease. Human Mutation, 32: 1232–1238. doi: 10.1002/humu.21566.
  6. DePaolo, J., Goker-Alpan, O., Samaddar, T., Lopez, G. and Sidransky, E. (2009), The association between mutations in the lysosomal protein glucocerebrosidase and parkinsonism. Movement Disorders, 24: 1571–1578. doi: 10.1002/mds.22538.

Presentations

  1. Thomas Dietzman MD, John DePaolo MD, PhD, Stefania Soria MD, Matthew J. Gillespie MD, Christopher Mascio MD, Yoav Dori MD PhD, Michael L. O’Byrne MD MSCE, Jonathan J. Rome MD, Andrew C. Glatz MD MSCE. Comparison of Short Term Outcomes In Patients With Single Ventricle Heart Disease Eligible for Inclusion of Antegrade Pulmonary Blood Flow as Part of the Bidirectional Glenn Circuit. American College of Cardiology National Meeting, New Orleans, LA, March 16, 2019.
  2. Bauser-Heaton H, Qureshi AM, Goldstein BH, Glatz AC, Nicholson GT, Meadows JJ, Depaolo J, McCracken C, Mossad E, Wilson E, Petit CJ. Percutaneous Patent Ductus Arteriosus Stenting Using the Carotid or Axillary Artery: A Multicenter Study from the Congenital Catheterization Research Collaborative. The Society for Cardiovascular Angiography and Interventions 2018 Scientific Sessions, San Diego, CA, April 26, 2018.
  3. J. DePaolo, Z. Wang, J. Guo, H. Zhang, C. Qian, J. Zabaleta, W. Liu. Androgen receptor acetylation at K618 by ARD1 is essential for dissociation from HSP90 in prostate tumorigenesis. American Association for Cancer Research Annual Meeting, New Orleans, LA, April 19, 2016.
  4. J. DePaolo, T. Samaddar, J. Vithayathil, N. Tayebi, E. Goldin, E. Sidransky, O. Goker-Alpan. LIMP-2 expression in fibroblast cell lines from subjects with Gaucher disease. 58th Meeting of the American Society of Human Genetics, Philadelphia, Pennsylvania, November 14, 2008.

Non Peer-Reviewed Publications

  1. Depaolo, J and Han, J. How the Opioid Epidemic looks to Doctors Caring for Babies and Transplanting Organs. The Philadelphia Inquirer – Philly.com. Available online: http://www.philly.com/philly/health/addiction/opioid-epidemic-penn-medicine-neonatal-intensive-care-organ-donors-medical-residents-20180221.html?arc404=true.
  2. DePaolo, J. Sorry, Medical Students, But You’re Not Entitled To Your Dream Job. Forbes/Opinion – The Apothecary. April, 2014. Available online: http://www.forbes.com/sites/theapothecary/2014/04/30/sorry-medical-students-but-youre-not-entitled-to-your-dream-job/#3403f52d532c.
  3. DePaolo, J., and Thomson, P. The Big Reset: Five years after the near-destruction of New Orleans, medical educators discuss the ongoing recovery. The New Physician, September, 2010.
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